MYELODYSPLASTIC SYNDROMES
Clinical trials for MYELODYSPLASTIC SYNDROMES explained in plain language.
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New pill shows promise for tough blood cancers in early trial
Disease control Recruiting nowThis early-phase study tests a new oral drug called BH-30236 in adults whose acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) has returned or not responded to prior treatments. The main goals are to check safety, find the right dose, and see if the drug ca…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: PHASE1 • Sponsor: BlossomHill Therapeutics • Aim: Disease control
Last updated Apr 28, 2026 20:21 UTC
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New low-dose weekly combo aims to tame bone marrow cancers with fewer side effects
Disease control Recruiting nowThis study tests a low-dose weekly combination of two approved drugs, decitabine and venetoclax, for people with bone marrow cancers like MDS, AML, and CMML. The goal is to see if this gentler schedule can keep patients on treatment longer by reducing side effects. About 91 adult…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: PHASE2 • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated Apr 28, 2026 20:21 UTC
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New drug combo aims to stop MDS return after transplant
Disease control Recruiting nowThis study tests whether giving a drug combination (decitabine and cedazuridine, or DEC-C) early can prevent myelodysplastic syndromes (MDS) from coming back after a stem cell transplant. About 209 adults who have had a transplant and still have tiny amounts of cancer cells (meas…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: PHASE1, PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Apr 28, 2026 20:20 UTC
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Last-Resort treatment option opens for blood cancer patients
Disease control AVAILABLEThis program offers galinpepimut-S, an experimental immune therapy, to individual patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) who have run out of standard treatments. It is for those who cannot join a clinical trial and have no other suitable opti…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Sponsor: Sellas Life Sciences Group • Aim: Disease control
Last updated Apr 28, 2026 20:20 UTC
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New combo therapy for blood cancer shows promise in early trial
Disease control Recruiting nowThis early-phase study tests a drug called venetoclax combined with standard chemotherapy for adults newly diagnosed with acute myeloid leukemia (AML) or advanced myelodysplastic syndrome (MDS). The goal is to find the safest dose and see how well the combination works. About 99 …
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: PHASE1 • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated Apr 28, 2026 20:20 UTC
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New drug combo targets Hard-to-Treat bone marrow disease
Disease control Recruiting nowThis early-stage study tests a new drug, SX-682, alone or with another drug (decitabine) in people with myelodysplastic syndrome (MDS), a bone marrow disorder. The main goal is to find a safe dose and check for side effects. About 151 adults whose disease has not responded to pri…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: PHASE1 • Sponsor: Syntrix Biosystems, Inc. • Aim: Disease control
Last updated Apr 28, 2026 20:19 UTC
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New genome test could change how we diagnose MDS
Knowledge-focused Recruiting nowThis study looks at whether a new whole genome test called ChromoSeq can work as well as standard genetic tests for people with myelodysplastic syndromes (MDS), a bone marrow disorder. About 60 adults with suspected or confirmed MDS will provide samples, and doctors will compare …
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Apr 28, 2026 20:21 UTC
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AI tool aims to speed up cancer trial enrollment for 50,000 patients
Knowledge-focused Recruiting nowThis study is testing whether an artificial intelligence (AI) tool can help connect cancer patients with the right clinical trials. Researchers will enroll up to 50,000 people with various cancers and use the AI to suggest trials based on their tumor's genetic markers. The goal i…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Sponsor: Massive Bio, Inc. • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC