New pill aims to tame tough blood cancers in early trial

NCT ID NCT06501196

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 31 times

Summary

This early-phase study tests an experimental oral drug called BH-30236 in adults whose acute myeloid leukemia or high-risk myelodysplastic syndrome has returned or not responded to prior treatments. The trial first finds a safe dose, then tests the drug alone or with another medicine (venetoclax). About 170 participants will be enrolled to check safety, how the body processes the drug, and whether it can shrink or control the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

  • Fred Hutchinson Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

  • Northwestern Medicine - Northwestern Memorial Hospital Galter Pavilion

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Roswell Park Cancer Institute

    RECRUITING

    Buffalo, New York, 14263, United States

  • Sarah Cannon Research Institute

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

  • Stanford Cancer Center

    RECRUITING

    Palo Alto, California, 94304, United States

  • Sylvester Comprehensive Cancer Center

    RECRUITING

    Miami, Florida, 33136, United States

  • The Ohio State University Wexner Medical Center - James Cancer Hosp

    RECRUITING

    Columbus, Ohio, 43210, United States

  • The University of Texas M.D. Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • University of California Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

  • University of Wisconsin Clinical Science Center

    RECRUITING

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.