Vitamin c boost: could high doses help fight bone marrow cancer?
NCT ID NCT07283900
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding high-dose vitamin C to a standard chemotherapy drug (azacitidine) can improve outcomes for adults with myelodysplastic syndrome (MDS), a bone marrow disorder. About 38 people with higher-risk MDS who haven't had much prior treatment will receive the combination intravenously. The goal is to see if the combo is safe and leads to remission or better survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
high-dose vitamin C (ascorbate) and azacitidine (Vidaza)
What this could lead to
If it works, this could point toward a more effective treatment for myelodysplastic syndrome, potentially improving remission rates and survival.
What could go wrong
This is a small, early-phase trial with only 38 participants, so results may not apply to everyone. High-dose vitamin C can cause side effects like kidney stones or infusion reactions.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Iowa
RECRUITINGIowa City, Iowa, 52242, United States