New Low-Dose combo aims to outsmart drug resistance in bone marrow disease
NCT ID NCT04187703
First seen May 20, 2026 · Last updated Jun 08, 2026 · Updated 4 times
Summary
This study tests a new way of giving two approved drugs (5-azacitidine and decitabine) to people with myelodysplastic syndromes (MDS) or related bone marrow disorders. Instead of standard high doses, the drugs are given in a low-dose, alternating schedule to reduce side effects and overcome drug resistance. The goal is to improve blood cell production and control the disease. About 20 adults will take part in this early-phase trial.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
RECRUITINGCleveland, Ohio, 44106, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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