New hope for Hard-to-Treat blood cancers: experimental combo targets relapsed AML and MDS

NCT ID NCT05986240

First seen Nov 11, 2025 · Last updated May 16, 2026 · Updated 22 times

Summary

This early-phase study tests a new drug called danvatirsen, first alone and then combined with venetoclax, in 38 adults whose acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) have returned or not responded to standard treatments. The goal is to see if the drug is safe and can shrink or control the cancer. Participants must be 18 or older and have no other approved treatment options.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M.D. Anderson Cancer Center, Department of Leukemia

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10467, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.