Could a 'Smart' transplant free blood cancer patients from lifelong drugs?

NCT ID NCT04678401

First seen Nov 01, 2025 · Last updated Apr 23, 2026 · Updated 25 times

Summary

This early-phase study tests a new stem cell transplant method for people with aggressive or returning acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). The approach uses specially engineered donor cells to help the body accept the transplant without needing lifelong immune-suppressing medications. About 30 participants will receive radiation, chemotherapy, and the experimental cell infusion to see if it is safe and effective.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.