New pill shows promise for tough blood cancers

NCT ID NCT05732103

Recruiting now Disease control Sponsor: Chordia Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an experimental drug called CTX-712 in people with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) that have come back or not responded to treatment. The drug is taken by mouth once or twice weekly. The trial aims to find the safest dose and see if it can shrink or control the cancer. About 225 adults will take part across multiple centers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CTX-712 (an experimental oral drug taken once or twice weekly)
What this could lead to: If it works, this could offer a new treatment option for people with hard-to-treat AML or MDS, potentially helping control the disease.
What could go wrong: This is an early-phase trial (Phase 1/2) with only 225 participants, so the drug may not work or could have serious side effects. It is not a cure and long-term benefits are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia myelodysplastic syndrome Myelodysplastic Syndromes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE MYELOID LEUKEMIA MYELODYSPLASTIC SYNDROMES

Contacts and locations

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Locations

Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States
Mayo Clinic Arizona
RECRUITING

Phoenix, Arizona, 85054, United States
Mayo Clinic Comprehensive Cancer Center
RECRUITING

Rochester, Minnesota, 55905, United States
Mayo Clinic Florida
RECRUITING

Jacksonville, Florida, 32224, United States
Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

Contact Email: •••••@•••••
The University of Rochester
RECRUITING

Rochester, New York, 14642, United States

Contact Email: •••••@•••••
The University of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
University of Virginia
RECRUITING

Charlottesville, Virginia, 22903, United States

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