New hope: drug combo after transplant may stop leukemia relapse in kids

NCT ID NCT05796570

First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 28 times

Summary

This study is testing whether giving two drugs, decitabine and filgrastim, after a stem cell transplant can help prevent leukemia or related blood cancers from coming back in children and young adults. About 37 participants with acute myeloid leukemia, myelodysplastic syndromes, or similar conditions will receive the drug combination over several cycles. The main goal is to see if this treatment plan is practical and safe to use after transplant.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.