MYELODYSPLASTIC SYNDROMES
Clinical trials for MYELODYSPLASTIC SYNDROMES explained in plain language.
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New drug may cut transfusions for rare bone marrow disorder
Disease control OngoingThis study tests a drug called luspatercept in 70 adults with a certain type of myelodysplastic syndrome (MDS) that causes severe anemia. The goal is to see if the drug can reduce or eliminate the need for regular red blood cell transfusions. Participants receive the drug by inje…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: PHASE3 • Sponsor: GWT-TUD GmbH • Aim: Disease control
Last updated Apr 28, 2026 21:35 UTC
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Experimental combo targets relapsed blood cancers after transplant
Disease control OngoingThis early-phase study tests a new treatment for people whose blood cancer (like AML or MDS) has returned after a donor stem cell transplant. The treatment combines a special type of donor immune cell infusion with an immunotherapy drug (ipilimumab) to help fight the cancer. The …
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Apr 28, 2026 21:35 UTC
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New drug combo aims to shield young transplant patients from deadly immune attack
Disease control OngoingThis study tests whether adding the drug vorinostat to standard care can prevent graft-versus-host disease (GVHD) in children, teens, and young adults receiving a bone marrow or blood stem cell transplant for blood cancers or disorders. About 43 participants will receive vorinost…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: PHASE1, PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Disease control
Last updated Apr 28, 2026 21:35 UTC
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Blood count mystery: 300 patients watched for early signs of bone marrow disease
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 300 people who have had low blood cell counts for at least 4 months but do not yet have myelodysplastic syndromes (MDS). The goal is to track how often these patients progress to MDS or related conditions. Researchers will monitor participants over time to bett…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Sponsor: The First Affiliated Hospital of Soochow University • Aim: Knowledge-focused
Last updated Apr 28, 2026 21:36 UTC
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Muscle weakness may predict transplant success in blood cancer patients
Knowledge-focused OngoingThis study looks at how blood cancer and stem cell transplants affect muscle function in 144 patients. Researchers want to see if muscle problems can help predict complications like infections, hospital stays, or survival. The goal is to better understand recovery and guide futur…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Apr 28, 2026 21:35 UTC