Cancer drug safety tracked in ongoing rollover trial

NCT ID NCT06788509

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study monitors long-term safety in 120 cancer patients who are already benefiting from treatments like JNJ-75348780, safimaltib, or ibrutinib in earlier trials. Participants have blood cancers, solid tumors, or prostate cancer. The goal is to track serious side effects over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

JNJ-75348780, safimaltib, and ibrutinib

What this could lead to

If successful, this study will confirm the long-term safety of these cancer drugs, supporting their continued use in patients who benefit.

What could go wrong

This is an early-phase rollover study focused on safety, not efficacy. It enrolls only patients already benefiting, so results may not apply to all. Side effects remain possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia B-cell chronic lymphocytic leukemia castration-resistant prostate carcinoma lymphoma, non-Hodgkin, familial metastatic prostate carcinoma myelodysplastic syndrome Myelodysplastic Syndromes neoplasm non-Hodgkin lymphoma Prostatic Neoplasms, Castration-Resistant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aidport Sp z o o

    Skorzewo, 60-185, Poland

  • Alexandra Hospital

    Athens, 115 28, Greece

  • Arensia Exploratory Medicine

    Tbilisi, Postal code 0112, Georgia

  • Arensia Exploratory Medicine

    Chisinau, 2025, Moldova

  • CHU Nantes

    Nantes, 44093, France

  • Chang Kung Memorial Hospital

    Kaohsiung City, 833, Taiwan

  • China Medical University Hospital

    Taichung, 404327, Taiwan

  • Clinica Univ. de Navarra

    Pamplona, 31008, Spain

  • Ghent University Hospital

    Ghent, 9000, Belgium

  • Hadassah University Hospita Ein Kerem

    Jerusalem, 9112001, Israel

  • Hopital Claude Huriez

    Lille, 59000, France

  • Hosp Univ Fund Jimenez Diaz

    Madrid, 28040, Spain

  • Hosp Univ Vall D Hebron

    Barcelona, 08035, Spain

  • Hosp Univ Vall D Hebron 1

    Barcelona, 08035, Spain

  • Hosp. Clinic de Barcelona

    Barcelona, 08036, Spain

  • Institut Gustave Roussy

    Villejuif, 94805, France

  • Linear Clinical Research Ltd

    Nedlands, 6009, Australia

  • Medical Center of Limited Liability Company Arensia Exploratory Medicine

    Kyiv, 01135, Ukraine

  • National Cheng Kung University Hospital

    Tainan, 704, Taiwan

  • National Hospital Organization Nagoya Medical Center

    Nagoya, 460-0001, Japan

  • National Taiwan University Hospital

    Taipei, 100, Taiwan

  • Pratia MCM Krakow

    Krakow, 30-727, Poland

  • Rambam Med.Center - Hematology Institute

    Haifa, 3109601, Israel

  • Rambam Medical Center

    Haifa, 3109601, Israel

  • Severance Hospital Yonsei University Health System

    Seoul, 03722, South Korea

  • St Bartholomews Hospital

    London, EC1A 7BE, United Kingdom

  • The Cancer Institute Hospital of JFCR

    Tokyo, 135 8550, Japan

  • University Hospitals Of Leicester Nhs Trust

    Leicester, Le1 5ww, United Kingdom

  • University Hospitals Plymouth NHS Trust

    Plymouth, PL6 8DH, United Kingdom

  • Uniwersyteckie Centrum Kliniczne Osrodek Badan Klinicznych Wczesnych Faz

    Gdansk, 80 214, Poland