New combo therapy before stem cell transplant shows promise for blood cancer patients
NCT ID NCT00544466
First seen Feb 26, 2026 · Last updated May 17, 2026 · Updated 10 times
Summary
This study tests a new way to prepare patients with leukemia or myelodysplastic syndromes for a donor stem cell transplant. It combines a precise type of radiation (helical tomotherapy) with two chemotherapy drugs (fludarabine and melphalan) to kill cancer cells and prevent rejection of the donor cells. The goal is to see if this approach is safe and helps patients survive longer. The study involves 75 participants and is in early phases (1 and 2).
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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City of Hope Medical Center
Duarte, California, 91010-3000, United States
Conditions
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