New antibody combo targets tough blood cancers

NCT ID NCT05428969

First seen Dec 10, 2025 · Last updated May 14, 2026 · Updated 23 times

Summary

This study tests a new drug called bexmarilimab, given with standard treatments, for people with certain blood cancers (MDS, CMML, or AML). The first part finds a safe dose, and the second part checks if the combination helps control the cancer. About 181 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Helsinki University Hospital

    Helsinki, 00029, Finland

  • Kuopio University Hospital

    Kuopio, 70210, Finland

  • Oulu University Hospital

    Oulu, 90029, Finland

  • Royal Cornwall Hospitals NHS Trust

    Truro, United Kingdom

  • Tampere University Hospital

    Tampere, 33520, Finland

  • The Christie NHS Foundation Trust

    Manchester, United Kingdom

  • UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

  • University of Texas, MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Yale Cancer Center

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.