New drug AG-946 aims to cut transfusions for MDS-Related anemia
NCT ID NCT05490446
First seen Oct 31, 2025 · Last updated May 08, 2026 · Updated 24 times
Summary
This study tests an experimental drug called AG-946 in about 87 adults with anemia due to lower-risk myelodysplastic syndromes (MDS). The goal is to see if the drug can raise hemoglobin levels or help people go without blood transfusions for at least 8 weeks. Participants receive the drug and are monitored for safety and effectiveness over several months.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Aberdeen Royal Infirmary - PPDS
Aberdeen, Aberdeen City, AB25 2ZN, United Kingdom
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Asan Medical Center - PPDS
Seoul, 05505, South Korea
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Attikon University General Hospital
Athens, Greece
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Azienda Ospedaliera Ordine Mauriziano di Torino
Turin, Piedmont, Italy
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C.H. Regional Reina Sofia - PPDS
Córdoba, 14004, Spain
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CHRU Lille
Lille, 59037, France
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CHU Angers
Angers, Maine-et-Loire, 49933, France
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Churchill Hospital-NHS Oxford
Oxford, OX3 7LE, United Kingdom
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Complejo Asistencial Universitario de Salamanca - H. Clinico
Salamanca, 37007, Spain
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David Geffen School of Medicine at UCLA
Los Angeles, California, 90024, United States
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Duke Adult Blood and Marrow Clinic
Durham, North Carolina, 27705, United States
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Edward H. Kaplan MD & Associates
Skokie, Illinois, 60076, United States
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Emad Ibrahim, MD, Inc.
Redlands, California, 92373, United States
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Fakultni nemocnice Ostrava
Ostrava, 708 52, Czechia
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Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
Milan, Lombardy, Italy
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Fondazione IRCCS Policlinico San Matteo di Pavia
Pavia, Lombardy, Italy
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Fondazione PTV Policlinico Tor Vergata
Roma, Italy
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Hippokration Hospital
Thessaloniki, Greece
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Hospital Universitario HM Sanchinarro - CIOCC
Madrid, 28050, Spain
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Hospital Universitario La Paz - PPDS
Madrid, 28046, Spain
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Hospital Universitario Virgen del Rocio - PPDS
Seville, 41013, Spain
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Hôpital Saint Louis
Paris, 75475, France
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Hôpital de La Conception
Marseille, Bouches-du-Rhône, 13010, France
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Innovative Clinical Research Institute Whittier
Lakewood, California, 90805, United States
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Istituto Clinico Humanitas
Rozzano, Lombardy, Italy
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Kings College Hospital
London, SE5 9RS, United Kingdom
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Kyungpook National University Hospital
Daegu, 41944, South Korea
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MTZ Clinical Research Powered by PRATIA - PPDS
Warsaw, Masovian Voivodeship, Poland
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Mayo Clinic Jacksonville - PPDS
Jacksonville, Florida, 32224, United States
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Medizinische Hochschule Hannover
Hanover, Lower Saxony, 30625, Germany
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Memorial Sloan Kettering Cancer Center
Long Island City, New York, 11101, United States
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Monash Health, Monash Medical Centre
Clayton, Victoria, 3168, Australia
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Ordensklinikum Linz GmbH Elisabethinen
Linz, Upper Austria, 4020, Austria
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Pratia Onkologia Katowice - PRATIA - PPDS
Katowice, Silesian Voivodeship, Poland
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SPZOZ MiSWiA z Warminsko-Mazurskim Centrum Onkologii w Olsztynie
Olsztyn, Warmian-Masurian Voivodeship, Poland
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Shaare Zedek Medical Center
Jerusalem, 9103102, Israel
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Smilow Cancer Hospital at Yale New Haven
New Haven, Connecticut, 06510, United States
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Tel Aviv Sourasky Medical Center PPDS
Tel Aviv, Israel
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The Catholic University of Korea, Seoul St. Mary's Hospital
Seoul, South Korea
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Universitatsklinikum Dusseldorf
Düsseldorf, North Rhine-Westphalia, 40225, Germany
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Universitatsklinikum Leipzig
Leipzig, Saxony, 04103, Germany
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University General Hospital of Patras
Pátrai, Greece
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University Hospital of Alexandroupolis
Alexandroupoli, Greece
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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Western General Hospital Edinburgh - PPDS
Edinburgh, EH24 2XU, United Kingdom
Conditions
Explore the condition pages connected to this study.