New transplant method aims to cut dangerous immune reaction in half-matched donors

NCT ID NCT05236764

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a stem cell transplant method that removes certain immune cells from the donor's blood to lower the chance of graft-versus-host disease (GvHD), a serious complication. It involves 3 patients with blood cancers or non-cancerous blood disorders who lack a perfectly matched donor. The goal is to see if this filtering approach allows safe transplant without long-term anti-rejection drugs.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MYELODYSPLASTIC SYNDROMES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acquired aplastic anemia acute myeloid leukemia aplastic anemia Bone Marrow Failure Disorders bone marrow failure syndrome chronic myelogenous leukemia, BCR-ABL1 positive Cytopenia hemoglobinopathy hemophagocytic syndrome inborn error of immunity inherited hemoglobinopathy Leukemia, Myelogenous, Chronic, BCR-ABL Positive Lymphohistiocytosis, Hemophagocytic myelodysplastic syndrome Myelodysplastic Syndromes non-Hodgkin lymphoma pancytopenia Precursor Cell Lymphoblastic Leukemia-Lymphoma Primary Immunodeficiency Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States