CYTOPENIA

This study tests whether the drug emapalumab can safely treat severe, prolonged low blood counts that sometimes occur after CAR-T cell therapy for lymphoma. Researchers will enroll 32 adults who developed this complication between 30-90 days after their CAR-T treatment. The goal …

This study is testing a targeted radiation drug called 177Lu-PSMA-617 in men with advanced prostate cancer that has spread to the bone marrow and caused low blood cell counts. The main goal is to see if the treatment is safe and effective for this specific group of patients who o…

This study is testing if giving a drug called emapalumab right after diagnosis can help children and young adults with severe aplastic anemia. Aplastic anemia is a rare condition where the bone marrow stops making enough blood cells. Researchers want to see if adding emapalumab e…

This study is testing an investigational drug called KER-050 (elritercept) to see if it can safely help the body make more healthy red blood cells in adults with lower-risk myelodysplastic syndromes (MDS) who have anemia. The main goals are to check the drug's safety and see if i…

This study aims to create a simple blood test that could replace painful bone marrow biopsies for diagnosing myelodysplastic syndrome (MDS) and other blood cell deficiencies. Researchers will collect blood samples from 1,500 adults who are already scheduled for bone marrow evalua…

This study aims to find people at risk for developing blood cancers and bone marrow failure syndromes before they get sick. Researchers will use advanced genetic testing on blood, bone marrow, and saliva samples from up to 2,000 participants. The goal is to identify early warning…