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New study uses DNA tests to catch blood cancers before they start

NCT ID NCT02958462

Recruiting now Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is looking at 2,000 people who have early warning signs of blood cancers or bone marrow failure. Researchers use a special genetic test (next generation sequencing) to find changes in cancer-related genes. The goal is to better understand who is at risk and to catch these conditions earlier, which could lead to faster treatment.

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Conditions

The condition(s) this trial relates to.

Bone Marrow Failure Disorders bone marrow failure syndrome clonal hematopoiesis of indeterminate potential Congenital Bone Marrow Failure Syndromes Cytopenia hematopoietic and lymphoid cell neoplasm hematopoietic and lymphoid system neoplasm hereditary neoplastic syndrome inherited hematologic cancer-predisposing syndrome monoclonal gammopathy of uncertain significance myelodysplastic syndrome myeloid neoplasm pancytopenia VEXAS syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BONE MARROW FAILURE SYNDROME CLONAL CYTOPENIA OF UNDETERMINED SIGNIFICANCE CLONAL EXPANSION CLONAL HEMATOPOIESIS OF INDETERMINATE POTENTIAL CYTOPENIA HEMATOLOGIC NEOPLASMS HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM HEREDITARY NEOPLASTIC SYNDROME IDIOPATHIC CYTOPENIA OF UNDETERMINED SIGNIFICANCE IDIOPATHIC DYSPLASIA OF UNCERTAIN SIGNIFICANCE INHERITED BONE MARROW FAILURE SYNDROME LOW RISK MYELODYSPLASTIC SYNDROME MYELOID MALIGNANCY

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Mayo Clinic in Arizona

    RECRUITING

    Scottsdale, Arizona, 85259, United States

    Contact Email: •••••@•••••

  • Mayo Clinic in Florida

    RECRUITING

    Jacksonville, Florida, 32224-9980, United States

    Contact Email: •••••@•••••

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Email: •••••@•••••

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