SEVERE APLASTIC ANEMIA
Clinical trials for SEVERE APLASTIC ANEMIA explained in plain language.
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New transplant method aims to cure blood diseases with fewer complications
Disease control Recruiting nowThis study is testing a modified stem cell transplant procedure for people with severe blood disorders like aplastic anemia. Researchers are adjusting how donor cells are collected and given to try to reduce serious side effects while still successfully replacing the patient's fa…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Apr 01, 2026 19:56 UTC
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New hope for rare blood disease patients lacking perfect donor matches
Disease control Recruiting nowThis study tests a bone marrow transplant method for people with severe aplastic anemia who don't have perfectly matched family donors. Researchers are using partially matched family donors along with specific medications after transplant to help the body accept the new cells. Th…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: Northside Hospital, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New transplant approach offers hope for devastating blood disease
Disease control Recruiting nowThis trial is testing a bone marrow transplant as the first treatment for people newly diagnosed with severe aplastic anemia, a rare disease where the body stops making enough blood cells. It aims to see if transplants using half-matched family members or unrelated donors can be …
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New transplant method aims to reduce dangerous side effects for rare blood disorders
Disease control Recruiting nowThis study is testing a modified stem cell transplant procedure for people with inherited bone marrow failure disorders like Fanconi anemia. The goal is to see if removing specific immune cells from the donor cells before transplant can reduce the risk of a serious complication c…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Massive trial opens lifeline with unapproved cord blood for desperate patients
Disease control Recruiting nowThis study provides access to cord blood units that are not yet FDA-approved for patients who need a transplant for blood cancers or other serious blood/immune disorders. It aims to see how well patients' immune systems recover after receiving these transplants and to monitor for…
Matched conditions: SEVERE APLASTIC ANEMIA
Sponsor: Center for International Blood and Marrow Transplant Research • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New approach aims to stop immune attack on bone marrow sooner
Disease control Recruiting nowThis study is testing if starting two oral medications (cyclosporine and eltrombopag) at home soon after diagnosis can help control severe aplastic anemia, a rare and serious blood disorder, while patients prepare for standard hospital treatment. Researchers want to see if this e…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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New hope for tough blood disorders: testing a repurposed drug
Disease control Recruiting nowThis study is testing whether the drug ruxolitinib can help adults whose immune system is attacking their bone marrow, causing severe blood diseases like aplastic anemia. Participants will take the pill twice daily for up to six months while researchers monitor their blood counts…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE1, PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Mar 16, 2026 15:27 UTC
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New hope for bone marrow failure: supercharged cord blood cells aim to fix transplant delays
Disease control Recruiting nowThis study is testing a new method for umbilical cord blood transplants in people with severe aplastic anemia or myelodysplastic syndrome (MDS), which are serious bone marrow diseases. Researchers are using specially prepared, expanded cord blood cells to try to help the transpla…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE1, PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Mar 02, 2026 15:21 UTC
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20-Year quest to map the future of rare blood diseases
Knowledge-focused Recruiting nowThis study aims to understand the long-term health journey of people with rare bone marrow failure diseases. Researchers will follow 1,000 participants, including some family members, for up to 20 years to see how these diseases and their treatments affect the body over time. The…
Matched conditions: SEVERE APLASTIC ANEMIA
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC