SEVERE APLASTIC ANEMIA
Clinical trials for SEVERE APLASTIC ANEMIA explained in plain language.
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Half-Matched stem cell transplant offers hope for children with blood disorders
Disease control Recruiting nowThis study tests a new type of stem cell transplant for children with severe blood disorders like sickle cell disease or aplastic anemia. The transplant uses stem cells from a parent or other half-matched family donor, which are specially processed to remove certain immune cells.…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: Johns Hopkins All Children's Hospital • Aim: Disease control
Last updated Jul 02, 2026 03:00 UTC
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New stem cell method aims to cut transplant risks
Disease control Recruiting nowThis study tests a new way to do stem cell transplants for people with severe aplastic anemia or other bone marrow failure diseases. Doctors give a smaller number of donor white blood cells along with the stem cells to try to reduce serious side effects. Up to 120 patients aged 4…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New cord blood treatment could transform transplants for bone marrow diseases
Disease control Recruiting nowThis study tests whether a new cord blood stem cell product, Omidubicel, can improve transplant outcomes for people with severe aplastic anemia or a related bone marrow disorder. Participants receive a combination of stem cells from a family member and specially processed cord bl…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE1, PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Cord blood transplants made more accessible for thousands with blood cancers
Disease control Recruiting nowThis study provides unlicensed cord blood units for transplant to children and adults with blood cancers, immune disorders, and other serious diseases. The goal is to see how well patients recover their white blood cells after the transplant. By making more cord blood units avail…
Matched conditions: SEVERE APLASTIC ANEMIA
Sponsor: Center for International Blood and Marrow Transplant Research • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New transplant approach aims to tame bone marrow failure
Disease control Recruiting nowThis phase 2 trial tests a bone marrow transplant using lower doses of chemotherapy and radiation to prepare the body, along with a drug called cyclophosphamide after transplant to prevent graft-versus-host disease. It enrolls 60 people with severe aplastic anemia or related bone…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New hope for rare blood disorder: Half-Matched transplants show promise
Disease control Recruiting nowThis study is for people with severe aplastic anemia, a rare condition where the bone marrow stops making enough blood cells, leading to serious infections and bleeding. It tests a bone marrow transplant from a half-matched family donor, followed by a drug to reduce complications…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: Northside Hospital, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:10 UTC
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Could starting pills earlier improve treatment for rare blood disorder?
Disease control Recruiting nowThis study tests whether starting two oral medications (cyclosporine and eltrombopag) earlier than usual is safe and feasible for people with severe aplastic anemia, a rare condition where the immune system attacks bone marrow. Participants aged 3 and older will take these pills …
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New hope for severe aplastic anemia: bone marrow transplant from partial matches shows promise
Disease control Recruiting nowThis study tests a bone marrow transplant from a partially matched donor (like a parent or sibling) for people newly diagnosed with severe aplastic anemia, a condition where the bone marrow stops making enough blood cells. Participants receive chemotherapy and immune-suppressing …
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New stem cell transplant could reduce immune suppression in bone marrow failure patients
Disease control Recruiting nowThis phase 2 trial tests a special stem cell transplant for people with inherited bone marrow failure disorders like Fanconi anemia. The transplant uses a technique to remove certain immune cells, aiming to reduce the need for long-term immune-suppressing drugs and lower infectio…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New hope for fanconi anemia: safer stem cell transplant trial opens
Disease control Recruiting nowThis study tests a stem cell transplant approach for people with Fanconi Anemia who don't have a perfectly matched donor. The goal is to see if using lower doses of chemotherapy before the transplant can reduce serious side effects. About 70 participants will receive a transplant…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New study maps best antibiotic steps for fever in cancer patients
Disease control Recruiting nowThis study tests a specific order of antibiotics for cancer patients who develop fever due to low white blood cells (febrile neutropenia). Twenty adults with blood cancers will receive a carbapenem first, then add vancomycin or linezolid if fever persists, and finally an antifung…
Matched conditions: SEVERE APLASTIC ANEMIA
Sponsor: Shanxi Bethune Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Ancient heat therapy tested to prevent post-transplant bladder pain
Prevention Recruiting nowThis study tests whether moxibustion, a traditional therapy that burns herbs near the skin, can prevent hemorrhagic cystitis (painful bladder inflammation) in 266 patients receiving stem cell transplants. Participants are randomly assigned to receive either standard care or stand…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: NA • Sponsor: Yi Zhang • Aim: Prevention
Last updated Jun 27, 2026 11:00 UTC
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20-Year study to track rare bone marrow diseases
Knowledge-focused Recruiting nowThis study follows people with acquired or inherited bone marrow failure for up to 20 years to learn how the diseases and treatments affect the body over time. Participants, aged 2 and older, will have regular check-ups and tests every 1 to 3 years. The goal is to better understa…
Matched conditions: SEVERE APLASTIC ANEMIA
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC