New combo therapy aims to cut blood transfusions in MDS patients

NCT ID NCT04798339

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 26 times

Summary

This study tests a combination of two drugs, canakinumab and darbepoetin alfa, in people with a type of bone marrow disorder called lower-risk myelodysplastic syndromes (MDS) who no longer respond to standard treatment. The goal is to see if the combination is safe and can reduce the need for red blood cell transfusions. About 13 adults will take part in this early-phase trial.

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Contacts and locations

Locations

  • Emory-Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.