New cell therapy aims to make bone marrow transplants safer
NCT ID NCT04013685
First seen Jun 03, 2026 · Last updated Jun 13, 2026 · Updated 4 times
Summary
This study tests a new treatment called Orca-T for people with advanced blood cancers like leukemia. Orca-T is a custom-made cell product from a donor that includes stem cells and special immune cells. The goal is to see if it can help the transplant work better and reduce serious side effects like graft-versus-host disease. About 155 participants will receive either Orca-T or standard transplant care.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope
Duarte, California, 91010, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Colorado Blood Cancer Institute
Denver, Colorado, 80218, United States
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Massachusetts
Boston, Massachusetts, 02114, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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OU Health Stephenson Cancer Center
Oklahoma City, Oklahoma, 73104, United States
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Oregon Health & Sciences University - Knight Cancer Institute
Portland, Oregon, 97239, United States
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Ronald Reagan UCLA Medical Center
Los Angeles, California, 90095, United States
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Sarah Cannon Research Institute
Nashville, Tennessee, 37203, United States
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Stanford Health Care
Stanford, California, 94305, United States
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The University of Kansas Hospital
Kansas City, Kansas, 66160, United States
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UC Davis
Sacramento, California, 95817, United States
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University of Chicago
Chicago, Illinois, 60637, United States
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University of Miami Hospital and Clinics - Sylvester Comprehensive Cancer Center
Miami, Florida, 33136, United States
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University of Michigan Health System - Michigan Medicine
Ann Arbor, Michigan, 48109, United States
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University of Texas MD Anderson Cancer Center
Houston, Texas, 77054, United States
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University of Utah - Huntsman Cancer Institute
Salt Lake City, Utah, 84112, United States
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Vanderbilt University
Nashville, Tennessee, 37232, United States
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Weill Cornell Medicine - New York-Presbyterian Hospital
New York, New York, 10021, United States
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Winship Cancer Institute - Emory University
Atlanta, Georgia, 30322, United States
Conditions
Explore the condition pages connected to this study.