New trial aims to make stem cell transplants safer for blood cancer patients
NCT ID NCT04888741
First seen May 07, 2026 · Last updated Jun 12, 2026 · Updated 9 times
Summary
This study tests two different drug combinations to prevent graft-versus-host disease (GVHD), a serious complication where donor cells attack the patient's body after a stem cell transplant. About 400 adults with blood cancers like leukemia or lymphoma will receive either thymoglobulin or a newer approach using post-transplant cyclophosphamide. The goal is to see which method helps patients live longer without GVHD or cancer relapse.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Addenbrookes Hospital
RECRUITINGCambridge, CB2 0QQ, United Kingdom
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Bristol Haematology and Oncology Centre
RECRUITINGBristol, BS2 8ED, United Kingdom
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Churchill Hospital
RECRUITINGOxford, OX3 7LE, United Kingdom
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Derriford Hospital
RECRUITINGPlymouth, PL6 8DH, United Kingdom
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Freeman Hospital
RECRUITINGNewcastle upon Tyne, NE7 7DN, United Kingdom
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Hammersmith Hospital
RECRUITINGLondon, W12 0HS, United Kingdom
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King's College Hospital
RECRUITINGLondon, SE5 9RS, United Kingdom
Contact
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Manchester Royal Infirmary
RECRUITINGManchester, M13 9WL, United Kingdom
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Nottingham City Hospital
RECRUITINGNottingham, NG5 1PB, United Kingdom
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Queen Elizabeth Hospital
RECRUITINGBirmingham, B15 2GW, United Kingdom
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Queen Elizabeth Hospital Glasgow
RECRUITINGGlasgow, G51 4TF, United Kingdom
Contact
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Royal Hallamshire Hospital
RECRUITINGSheffield, S102JF, United Kingdom
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St Jame's University Hospital
RECRUITINGLeeds, LS9 7TF, United Kingdom
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The Christie
RECRUITINGManchester, M20 3QH, United Kingdom
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The Royal Marsden Hospital
RECRUITINGSutton, SM2 5PT, United Kingdom
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University College London Hospital
RECRUITINGLondon, NW1 2BU, United Kingdom
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University Hospital of Wales
RECRUITINGCardiff, Wales, CF14 4XW, United Kingdom
Contact
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.