New drug combo aims to stop MDS return after transplant
NCT ID NCT04742634
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving a two-drug combination (decitabine and cedazuridine, or DEC-C) early can prevent myelodysplastic syndromes (MDS) from coming back after a stem cell transplant. About 209 adults with MDS who have tiny amounts of cancer cells left after transplant will receive DEC-C. The goal is to see if this approach lowers relapse risk and improves survival.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
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