New pill takes on hard-to-treat blood cancers in first human trial

NCT ID NCT06146257

First seen Oct 01, 2025 · Last updated May 12, 2026 · Updated 31 times

Summary

This early-phase study tests an experimental oral drug, GLB-001, in about 48 adults with acute myeloid leukemia or high-risk myelodysplastic syndromes that returned or didn't respond to prior therapy. The main goals are to find a safe dose and check for side effects. Researchers will also look for signs that the drug is working against the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alliance for Multispecialty Research, LLC

    TERMINATED

    Merriam, Kansas, 66204, United States

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Memorial Sloan Kettering Cancer Center-David H. Koch Center

    TERMINATED

    New York, New York, 10021, United States

  • Roswell Park Comprehensive Cancer Center

    TERMINATED

    Buffalo, New York, 14263, United States

  • University of California Irvine

    TERMINATED

    Irvine, California, 92697, United States

  • University of Kansas Medical Center Research Institute, Inc.

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas M. D. Anderson Cancer Center

    TERMINATED

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.