ACUTE ISCHEMIC STROKE

This study is testing if a new, faster emergency room setup helps people recover better from a major type of stroke. It compares a 'one-stop' room where diagnosis and treatment happen immediately to the standard process where patients are moved between different hospital areas. T…

This study is for people who have just had a major stroke caused by a large blood clot. After doctors remove the main clot, some patients still have a severely narrowed artery that could cause another stroke. This trial will test if immediately placing a small mesh tube (stent) t…

This study aims to find the best dose of a traditional Chinese herbal granule called Xinglou Chengqi to help people recover from a recent ischemic stroke. It will involve 60 patients who had a stroke within the past week and have specific traditional Chinese medicine symptoms. Re…

This study is testing if giving a clot-dissolving drug (rhPro-UK) by IV before a standard clot-removal surgery helps people recover better from a major stroke. It focuses on patients who arrive for treatment 4.5 to 24 hours after their stroke symptoms began, which is later than t…

This study is testing whether delivering a clot-busting drug directly into a blocked brain artery can help people recover better from a specific type of stroke. It will involve about 488 adults who have had a stroke caused by a blockage in a medium-sized brain vessel within the l…

This early study is testing a new drug called RK-4, injected directly into the brain through the skull, for people who have just had a severe stroke and cannot receive standard treatments. The main goal is to see if this injection is safe and how the body handles the drug, while …

This study is testing whether adding a drug called human urinary kallidinogenase to the standard stroke treatment (reteplase) helps patients recover better. It will involve 220 adults who have just had an ischemic stroke and can receive treatment within 4.5 hours. The main goal i…

This study tests whether the clot-busting drug tenecteplase can help stroke patients who arrive at the hospital 4.5 to 24 hours after symptoms begin, when the standard mechanical clot removal procedure isn't available. Researchers will compare giving the drug against standard med…

This study is testing whether a smartphone app that provides personalized weather-related health warnings and helps manage risk factors can reduce the chance of a second stroke. It will involve over 10,000 people who have recently had a stroke. The goal is to see if this digital …

This study is testing a new medical device called the iNstroke catheter to see how well and safely it can remove blood clots from the brain during a stroke. Doctors will use the thin, flexible tube to suction out blockages in patients who have had a stroke within the last 24 hour…

This study is testing whether an experimental drug called J147 can help protect the brain and improve recovery after a stroke. Researchers will give J147 or a placebo to 196 stroke patients immediately after they undergo surgery to remove the blood clot causing their stroke. The …

This study is testing an experimental drug called TAK-755 in adults who have just had an ischemic stroke, which is caused by a blood clot blocking blood flow to the brain. The main goals are to see if the drug is safe and if it helps people recover their ability to perform daily …

This study is testing if adding a blood-thinning drug called tirofiban after emergency stroke treatment helps patients recover better. It will involve 564 adults in China who have just had a major stroke caused by a blocked artery and have already received clot-busting medicine a…

This study is testing whether a clot-busting drug called tenecteplase can help people who have a stroke but don't know when it started, such as when they wake up with symptoms. About 352 participants will be randomly assigned to receive either the drug plus standard care or stand…

This early-stage study is testing whether a nasal spray containing tiny particles from human fat stem cells can help the brain heal after a stroke. The spray is given alongside standard care to see if it's safe and if it can improve recovery of movement and thinking. The trial wi…

This trial aims to find the best way to treat people having a stroke caused by a blood clot when they also have high blood pressure. Currently, doctors must lower a patient's blood pressure before giving the standard clot-busting drug, which can cause treatment delays. This study…

This study is testing a new medical tool called the SOFIA Flow 88 Aspiration Catheter. It is designed to quickly remove large blood clots from the brain during a major stroke, with the goal of restoring blood flow and limiting permanent damage. The research will measure how safe …

This early-stage study is testing the safety of a two-drug combination (chlorpromazine and promethazine) given before a standard clot-removal procedure for stroke. The goal is to see if this 'hibernation-like' therapy is safe and might help reduce brain damage. The study will inv…

This study is testing a new AI computer system called LingBao, designed to help doctors quickly decide the best treatment for patients having a stroke caused by a blood clot. At 20 major stroke centers, half will use the AI tool alongside standard care, while the other half will …

This study aims to compare how well two existing stroke medications help patients recover from mild-to-moderate strokes. Researchers will follow 600 stroke patients in real hospital settings to see which drug leads to better recovery outcomes. The study will look at safety, effec…

This study is testing if adding a cholesterol-lowering drug called a PCSK9 inhibitor to standard treatment helps people recover better after a severe stroke. It will involve about 478 adults who have just had a major stroke and a procedure to remove the clot. The main goal is to …

This study is testing a new treatment called RK-4 for people who have just had a severe, large stroke and cannot receive or do not respond to standard clot-busting treatments. Researchers will inject RK-4 directly into the skull bone marrow over three days to see if it is safe an…

This trial is for people who have a severe stroke caused by a large blood clot in the brain but arrive at the hospital 24 to 72 hours after symptoms begin. It will test if performing a minimally invasive procedure to remove the clot, on top of standard medical care, leads to bett…

This study looks back at past patient records to see which treatment works best for a specific type of stroke that often gets worse after it starts. It compares a standard clot-busting drug (IVT) against different types of blood-thinning pills (SAPT or DAPT). The goal is to find …

This study tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) helps people recover better after surgery to remove a stroke-causing blood clot. Researchers will enroll 424 stroke patients who recently had the surgery and randomly assign some t…

This study is testing whether adding a medication called eptifibatide helps people recover better after receiving standard clot-busting treatment for a stroke. It focuses on patients who get treatment 4.5 to 24 hours after symptoms begin and who aren't improving well. The main go…

This study is testing a rapid bedside blood test, similar to a pregnancy test, to see if it can quickly and accurately tell if a child is having a specific type of stroke caused by a major blood clot. Researchers will enroll 250 children who arrive at the emergency room with sudd…

This study is testing whether a smartphone app can help people who have had a stroke prevent a second one. The app gives users personalized advice based on their specific health risks, like blood pressure or blood sugar. Researchers will follow about 5,000 stroke survivors for a …

This study is testing if a smartphone app can help prevent a second stroke. The app will send personalized warnings about weather-related health risks, like extreme temperatures, to people who have recently had a stroke. Researchers will enroll over 5,000 patients to see if using…

This study aims to understand why some stroke patients get worse after a successful procedure to remove a blood clot. Researchers will use a non-invasive brain ultrasound on 100 patients to measure blood flow after the procedure. The goal is to find patterns that could help docto…

This study looks back at the medical records of 500 patients who had emergency surgery to remove a blood clot from the brain after a stroke. Researchers want to see if patients who were put fully to sleep (general anesthesia) had different survival and recovery rates than those w…

This study aims to understand if changes in a gene called GGCX affect how well people recover after a stroke. Researchers will collect blood samples from 1,500 stroke patients and follow their health for a year to see if the gene is linked to having another stroke, bleeding probl…