Could a cholesterol drug boost stroke recovery?

NCT ID NCT07174375

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether adding a PCSK9 inhibitor (a cholesterol-lowering drug) to standard care helps people recover better after a stroke caused by a blocked artery. About 478 adults who had a stroke and received a procedure to reopen the blocked vessel will be randomly assigned to get the drug or not. The main goal is to see if more people achieve a good functional outcome (able to live independently) at 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PCSK9 inhibitors (Evolocumab or Alirocumab)

What this could lead to

If successful, this could show that adding a cholesterol-lowering drug after stroke treatment improves recovery and reduces the chance of another stroke.

What could go wrong

This is an early-to-mid stage trial, so results may not be conclusive. The drug may not provide additional benefit over standard care, and there are risks like injection site reactions or muscle pain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dongguan Donghua Hospital

    Dongguan, Guangdong, China

  • Dongguan People's Hospital

    Dongguan, Guangdong, China

  • Fujian Medical University Union Hospital

    Fuzhou, Fujian, China

  • Ganzhou City People's Hospital

    Ganzhou, Jiangxi, China

  • Haikou People's Hospital

    Haikou, Hainan, China

  • Hainan Provincial Hospital of Traditional Chinese Medicine

    Haikou, Hainan, 570100, China

  • Hainan Provincial People's Hospital

    Haikou, Hainan, China

  • Hengzhou City People's Hospital, Guangxi

    Hengzhou, Guangxi (Autonomous Region), China

    Contact Phone: •••-•••-••••

  • Heyuan People's Hospital

    Heyuan, Guangdong, China

  • Huadu District People's Hospital of Guangzhou

    Guangzhou, Guangdong, China

  • Nanfang Hospital of Southern Medical University

    Guangzhou, Guangdong, China

  • The Second Affiliated Hospital of Hainan Medical University

    Haikou, Hainan, China

    Contact Phone: •••-•••-••••