Could a new drug help stroke patients recover better?

NCT ID NCT07495722

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage study tests the safety of a drug called pegcetacoplan (Empaveli) in 20 adults who have had a stroke from a large clot and already had a procedure to remove it. The drug aims to reduce swelling and inflammation that can occur when blood flow returns. Participants receive three doses and are followed for 90 days to check for side effects and recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Pegcetacoplan (Empaveli)
What this could lead to
If safe, this could point toward a treatment that reduces brain swelling and improves recovery after a stroke.
What could go wrong
This is a very early Phase 1 safety trial with only 20 people. It is not designed to prove the drug works, and side effects or lack of benefit are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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