Could a common drug prevent brain swelling after stroke?
NCT ID NCT07528456
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the drug butylphthalide can reduce brain swelling in people who have had a severe stroke and undergone a procedure to reopen a blocked artery. About 100 adults will receive either the drug or a placebo for up to 14 days. Researchers will measure changes in spinal fluid and brain scans to see if the drug helps.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
butylphthalide
What this could lead to
If it works, this could point toward a new way to reduce dangerous brain swelling after a stroke, potentially improving recovery.
What could go wrong
This is a small, early-phase trial with only 100 people. The drug may not reduce swelling better than placebo, and side effects are possible.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dongguan People's Hospital
Dongguan, Guangdong, China
Contact
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Ganzhou People's Hospital
Ganzhou, Jiangxi, China
Contact
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Haikou People's Hospital
Haikou, Hainan, China
Contact
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Hainan Provincial Hospital of Traditional Chinese Medicine
Haikou, Hainan, China
Contact
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Heyuan People's Hospital
Heyuan, Guangdong, China
Contact
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Nanfang Hospital of Southern Medical University
Guangzhou, Guangdong, 510515, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Qingyuan People's Hospital
Qingyuan, Guangdong, China
Contact
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The Fourth Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China
Contact
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The Second Affiliated Hospital of Hainan Medical University
Haikou, Hainan, China
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Yuebei People's Hospital
Shaoguan, Guangdong, China
Contact