Brain edema
MONDO:0006684Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see hypoxia, brain). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of csf flow (e.g., obstructive hydrocephalus). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
22 clinical trials for this condition and its sub-types.
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Early surgery may save lives in severe stroke patients
Disease control Recruiting nowThis study tests whether performing skull surgery early, before dangerous brain swelling occurs, can improve outcomes for people who have had a severe stroke and are at high risk of swelling. About 380 adults aged 18–75 will be randomly assigned to receive either early surgery pl…
Phase: NA • Sponsor: Xuanwu Hospital, Beijing • Aim: Disease control
Last updated Jun 27, 2026 08:14 UTC
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Egg yolk powder could help heal traumatic brain injuries
Disease control Recruiting nowThis study tests whether a special egg yolk powder called Salovum can help people with severe traumatic brain injury. Half of the 20 participants get Salovum, the other half get a placebo. Researchers will measure brain pressure, oxygen levels, and inflammation to see if the trea…
Phase: PHASE2 • Sponsor: Peter Siesjö • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Which anesthesia is safer for your brain during tumor surgery?
Knowledge-focused Recruiting nowThis study compares two common anesthesia methods—inhaled gases (sevoflurane or desflurane) versus intravenous propofol—in 84 adults having brain tumor surgery. Researchers will measure brain oxygen levels, swelling, and thinking skills after surgery to see which approach better …
Phase: PHASE4 • Sponsor: Georgia Tsaousi • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC