Skull injection could bypass brain barrier for stroke patients
NCT ID NCT07514949
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tests whether a drug called RK-4 can be safely injected through the skull into the brain of people having a severe stroke. Only 6 participants will receive the injection once a day for 3 days, using a special device. The main goal is to see if the procedure is feasible and safe, not yet to prove it improves outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
RK-4 (a neuroprotective drug)
What this could lead to
If successful, this could point toward a new way to deliver stroke treatments directly to the brain, potentially improving recovery for patients who cannot have standard clot-removal therapy.
What could go wrong
This is a very early, tiny pilot study with only 6 people. It is designed mainly to check safety and whether the injection method works, not to prove the drug helps. There are risks like infection, bleeding, or the procedure being too uncomfortable.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beijing Tiantan Hospital
Beijing, China