ACUTE ISCHEMIC STROKE

This study tested whether a one-time intravenous infusion of donor stem cells (mesenchymal stem cells) could help people who recently had a severe ischemic stroke. Participants were adults aged 18 to 80 who had a stroke within the past 9 days. The goal was to see if the cells cou…

This study was designed to test a new device called the CEREGLIDE 92 catheter for removing blood clots in people having a severe stroke. It aimed to see if the device could restore blood flow on the first try. However, the study was withdrawn before any volunteers were enrolled, …

This study tests if infusing a cooled magnesium solution directly into the brain's arteries after removing a clot can improve recovery for people with severe stroke. About 42 adults aged 18-80 with a large vessel blockage in the front part of the brain will be enrolled. The goal …

This study tests a special stent (CGuard Prime) placed in the neck artery to treat acute ischemic stroke. It involves 15 adults with severe stroke symptoms and blocked arteries. The goal is to see if the stent is safe and helps patients recover better by 90 days.

This study tests an experimental drug called redasemtide in 680 adults who have had a stroke caused by a blocked blood vessel. Participants receive either the drug or a placebo within 25 hours of their stroke. The goal is to see if the drug helps people recover better and have le…

This study planned to test a device called the SOFIA Flow 88 Aspiration Catheter for removing blood clots in people having a severe stroke. The goal was to see if it could safely restore blood flow to the brain. However, the study was withdrawn before enrolling any participants, …

This study tests whether giving the steroid methylprednisolone along with standard clot-removal treatment can reduce deaths in people who have had a major stroke. About 928 adults with large strokes will be randomly assigned to receive either the steroid or a placebo. The main go…

This study compares a minimally invasive procedure (endovascular treatment) to standard care for 300 adults aged 18-80 who have had a mild stroke caused by a blocked large artery in the front part of the brain. Participants must be treated within 24 hours of symptoms starting. Th…

This study aimed to see if adding the antibiotic minocycline to standard stroke treatment could help people recover better after a severe stroke caused by a blocked large artery. The plan was to give some patients minocycline for 21 days and others a placebo, then compare their d…

This study tests whether giving the clot-busting drug tenecteplase directly into the brain artery after mechanical clot removal is safe and feasible for people with acute ischemic stroke. About 40 adults who had a large-vessel blockage stroke within the last 4.5 to 24 hours will …

This study looks at 20 adults who recently had a stroke to compare two types of brain scans: CT and PET. The goal is to see how well PET scans measure blood flow and brain cell activity compared to standard CT scans. Participants will get both scans within a week of their stroke,…