ACUTE ISCHEMIC STROKE

This study aimed to test a new medical device called CEREGLIDE 92 for removing blood clots from the brain during acute ischemic stroke. The device would be used in a procedure called neurothrombectomy to restore blood flow to the brain. The trial was withdrawn before any particip…

This study aimed to see if adding the antibiotic minocycline to standard emergency surgery for a severe stroke could help patients recover better. It planned to enroll adults who had a major stroke caused by a large blocked artery and were undergoing a procedure to remove the clo…

This study aims to find the safest and most effective blood-thinning medication for patients experiencing a severe stroke caused by a blockage in both the neck and brain arteries. It will compare two drugs, Tirofiban and intravenous Aspirin, in 240 patients who receive emergency …

This early study is testing the safety and initial effectiveness of a new carotid stent called CGuard Prime™ in patients who are having an acute ischemic stroke. It involves 15 adult patients with a significant blockage in their neck artery who are actively experiencing a stroke.…

This large study is testing if adding the steroid methylprednisolone to the standard emergency procedure to remove a blood clot (thrombectomy) can help people who have had a severe stroke with significant brain damage. It will enroll 928 adults who have had a major stroke in the …

This first-in-human study is testing a new medical device that cools the brain after a stroke. It is used right after doctors remove a blood clot from the brain. The goal is to see if cooling the brain for 30 minutes is safe and can help protect brain tissue, potentially leading …

This study is testing whether giving a clot-dissolving drug directly into the brain's arteries after a clot removal procedure is safe and helpful for stroke patients. It involves 40 people who have had a major stroke caused by a large blood clot. The goal is to see if this extra …

This study is testing a new approach to protect the brain during emergency stroke surgery. After doctors remove a blood clot, they will infuse a cooled magnesium solution directly into the affected artery. The goal is to see if this added step is safe and helps more patients rega…

This study is testing whether an investigational drug called redasemtide can help adults recover better after an acute ischemic stroke. It will compare the drug to a placebo in about 680 participants, including those who can and cannot receive standard clot-busting treatments. Th…

This study is testing a web-based tool designed to help family members make difficult decisions about continuing or withdrawing life support for loved ones with severe brain injuries. The tool provides information and support to prepare families for conversations with doctors. Re…