ACUTE ISCHEMIC STROKE

This study tested whether a new drug called elezanumab could help people recover better after a stroke. About 120 participants who had just experienced a stroke received either the drug or a placebo through IV infusions every 4 weeks for a full year. Researchers measured whether …

This completed Phase 3 trial tested whether trimetazidine, a medication typically used for chest pain, could help people recover from an ischemic stroke (caused by a blocked blood vessel in the brain). The study involved 60 adults who had recently suffered a stroke, and it aimed …

This early-stage study tested the safety and initial effectiveness of a new injection called HRS-7450 for people who recently had an ischemic stroke (a stroke caused by a blocked blood vessel in the brain). The trial involved 64 participants who received the drug within 24 hours …

This study tested whether giving a stroke medication called butylphthalide very early (within 3 hours of symptoms) leads to better recovery than giving it a bit later (3-6 hours). It involved 204 adults who had just suffered a stroke. The goal was to find the best treatment windo…

This study aimed to find out if using a special balloon-tipped catheter is better than a standard one for emergency clot-removal procedures in stroke patients. It involved 110 adults who had a major stroke caused by a large blocked artery in the brain. Researchers randomly assign…

This study tested a new method to protect the brain after successful removal of a stroke-causing blood clot. Researchers temporarily interrupted and restored blood flow to the brain using a special balloon catheter immediately after the clot was removed. The goal was to find the …

This study looked at patients who had a severe stroke with a large area of brain damage. It aimed to find out which factors help predict if a patient will recover well after having a procedure to remove the blood clot within 24 hours of stroke symptoms starting. The goal is to he…

This large study observed how a clot-dissolving drug called non-immunogenic staphylokinase worked for patients having a stroke in real hospital settings. It involved over 23,000 adults who received the drug within 4.5 hours of their stroke symptoms starting. The main goal was to …

This study tested whether giving an intravenous antioxidant drug called N-acetylcysteine (NAC) could help people recover better after a stroke. NAC is already FDA-approved for treating acetaminophen overdose. The trial involved 4 adults who had a recent ischemic stroke and were n…

This study tested whether adding an anti-inflammatory drug called sodium sivelestat to the standard mechanical clot removal procedure could improve recovery for people having a major stroke. It involved 20 patients who had a large blood vessel blockage in the brain. The goal was …

This study tested whether a new drug called LT3001 is safe and effective for treating recent ischemic strokes. The trial involved 89 patients who received either the drug or a placebo within 24 hours of stroke symptoms starting. Researchers compared safety outcomes and how well p…

This study tested if a simple, non-invasive treatment could help people recover from a major stroke. Researchers gave 40 stroke patients gentle electrical stimulation to the ear, targeting a nerve linked to reducing inflammation. They compared this to a sham treatment to see if i…

This study aimed to find the best time to remove breathing tubes after a major stroke procedure. Researchers compared taking the tube out early (within 6 hours) versus later (6-12 hours) in 174 patients. The goal was to see which timing led to better recovery, fewer complications…

This study tested whether adding the drug tirofiban after successful mechanical removal of a stroke-causing blood clot helps patients recover better. It involved 1380 adults who had a major stroke and whose clot was successfully removed within 24 hours. Patients were randomly giv…

This study tested a new drug called LT3001 for people who recently had an ischemic stroke (caused by a blocked blood vessel in the brain). The main goal was to check if the drug is safe and doesn't cause dangerous bleeding in the brain, compared to a placebo. It involved 24 patie…

This study compared two common blood pressure medications (nicardipine and labetalol) to see which one works faster to lower dangerously high blood pressure in stroke patients. Researchers wanted to know which drug helps patients reach safe blood pressure levels more quickly so t…

This study tested a new medicine called SHPL-49, given as an injection for 7 days, to see if it could help people recover better from a recent stroke. It involved 270 adults who had a stroke within the last 8 hours. Researchers compared two different doses of the medicine to a pl…

This study aimed to find the best emergency treatment for a severe, life-threatening stroke caused by a blockage in a major brain artery. Researchers compared two approaches for 345 patients: giving a standard clot-busting drug (IV alteplase) before performing a surgical procedur…

This study tested if raising a patient's legs (while keeping the head level) is a safe and practical way to improve blood flow to the brain after a moderate stroke. The goal was to see if this simple positioning could help limit brain damage. Researchers enrolled 50 stroke patien…

This study tested whether a clot-dissolving drug (rhTNK-tPA) could help patients recover better from a certain type of stroke, even if given much later than usual—between 4.5 and 24 hours after symptoms start. It involved 570 patients across China who had a stroke but not a major…

This study tested the safety of an experimental drug called PP-007 in people who had just suffered a stroke caused by a blood clot. The 24 participants received two doses of the drug in addition to their standard stroke treatments, like clot-busting medication or removal. Researc…

This study tested a new medical device called the Millipede System for treating severe strokes caused by large blood clots. Doctors used it to try to quickly remove the clot and restore blood flow to the brain in 246 patients. The main goals were to see how well the device worked…

This study tested whether an artificial intelligence (AI) tool could help doctors and radiographers read emergency brain CT scans more accurately and quickly. Thirty-three clinicians reviewed 150 scans, some with and some without the AI's help, to see if it improved their speed, …

This study tested whether applying a special elastic tape (kinesio taping) helps people recover arm and hand movement after a recent stroke. 26 adults who had a stroke within the last 6 months were randomly assigned to get either the real therapeutic tape or a fake tape that didn…

This study aimed to find better ways to predict dangerous complications like brain swelling and bleeding after a stroke. Researchers followed 213 stroke patients, analyzing their blood and brain scans, and also studied a mouse model. The goal was to link specific blood markers an…

This early-stage study tested the safety of an experimental drug called LT3001, which is being developed for acute ischemic stroke. Researchers gave the drug to 65 healthy volunteers to check for side effects and see how it interacts with common blood-thinning medications like as…