Could a drug calm brain inflammation after stroke? new trial aims to find out

NCT ID NCT07263776

Ongoing Disease control Sponsor: Capital Medical University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding an interleukin-6 receptor inhibitor (a drug that reduces inflammation) to standard emergency stroke treatment helps people recover better after a severe stroke caused by a large blood clot in the front part of the brain. About 692 adults who are eligible for emergency clot removal will receive either the drug or a placebo. The main goal is to see if the drug improves disability levels three months after the stroke.

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Conditions

The condition(s) this trial relates to.

ischemic stroke large artery stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE ISCHEMIC STROKE

Contacts and locations

Locations

Beijing Red Cross Emergency Medical Center

Beijing, China
Binzhou Medical University Hospital

Binzhou, Shandong, China
Daliuta Experimental District People's Hospital of Shenmu City

Yulin, Shanxi, China
Henan Provincial People's Hospital

Zhengzhou, Henan, China
Huixian People's Hospital

Xinxiang, Henan, China
Jiaozuo No.2 People's Hospital

Jiaozuo, Henan, China
Jiaxing First Hospital

Jiaxing, Zhejiang, China
Jincheng People's Hospital

Jincheng, Shanxi, China
JingDong ZhongMei Hospital

Langfang, Hebei, China
Jun County People's Hospital

Hebi, Henan, China
Lingshan County People's Hospital

Qinzhou, Guangxi, China
Linshu Country People's Hospital

Linyi, Shandong, China
Linyi People's Hospital

Linyi, Shandong, China
Lishui Central Hospital

Lishui, Zhejiang, China
Luoyang Central Hospital

Luoyang, Henan, China
Mengjin County People's Hospital

Luoyang, Henan, China
Nantong First People's Hospital

Nantong, Jiangsu, China
Nanyang Central Hospital

Nanyang, Henan, China
Nanyang Nanshi Hospital

Nanyang, Henan, China
Nanyang Second People's Hospital

Nanyang, Henan, China
Ningbo Medical Center Lihuili Hospital

Ningbo, Zhejiang, China
Ningbo NO.2 Hospital

Ningbo, Zhejiang, China
Ningling County People's Hospital

Shangqiu, Henan, China
People's Hospital of Dongying

Dongying, Shandong, China
Puyang Oilfield General Hospital

Puyang, Henan, China
Qingdao Huangdao District Hospital of Traditional Chinese Medicine

Qingdao, Shandong, China
Shangqiu No.1 People's Hospital

Shangqiu, Henan, China
Shanxi Bethune Hospital

Taiyuan, Shanxi, China
Shanxi Medical University First Hospital

Taiyuan, Shanxi, China
Shenzhen Longhua District People's Hospital

Shenzhen, China
Si Country People's Hospital

Suzhou, Anhui, China
Suixi County Hospital

Suzhou, Anhui, China
Suzhou Hospital of Anhui Medical University

Suzhou, Anhui, China
Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University

Taizhou, Zhejiang, China
Tanghe County People's Hospital

Nanyang, Henan, China
Tangshan Workers Hospital

Tangshan, Hebei, China
The First Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, China
The First Affiliated Hospital of Henan Medical University

Xinxiang, Henan, China
The People's Hospital of Anyang

Anyang, Henan, China
The People's Hospital of Xianyang

Xianyang, Shanxi, China
The second Hospital of Qinhuangdao

Qinhuangdao, Hebei, China
Tianyou Hospital Affliated to Wuhan University of Science &Technology

Wuhan, Hubei, China
Wenzhou People's Hospital

Wenzhou, Zhejiang, China
Xiangyang No.1 People's hospital

Xiangyang, Hubei, China
Xihua County People's Hospital

Zhoukou, Henan, China
Xing'an league People's Hospital

Xing’an, Inner Mongolia, China
Xinxiang Central Hospital

Xinxiang, Henan, China
Xuanwu Hospital, Capital Medical University

Beijing, 100053, China
Yiyuan Country People's Hospital

Zibo, Shandong, China
Yueqing People's Hospital

Yueqing, Zhejiang, China
Yutian Hospital

Tangshan, Hebei, China
Zhangzhou Municipal Hospital

Zhangzhou, Fujian, China
Zhongxiang Traditional Chinese Medical Hospital

Zhongxiang, Wuhan, China
Zibo Central Hospital

Zibo, Shandong, China

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