Could a targeted clot-buster boost stroke recovery?

NCT ID NCT06781385

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This study tests whether giving the clot-busting drug tenecteplase directly into the brain artery after mechanical clot removal is safe and feasible for people with acute ischemic stroke. About 40 adults who had a large-vessel blockage stroke within the last 4.5 to 24 hours will receive the drug during the clot removal procedure. The goal is to see if this approach can improve outcomes without increasing bleeding risk.

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Contacts and locations

Locations

  • Atrium Health Neurosciences Institute

    Charlotte, North Carolina, 28207, United States

Conditions

Explore the condition pages connected to this study.