Chilled magnesium may boost stroke recovery in new trial

NCT ID NCT07163299

ENROLLING_BY_INVITATION Disease control Sponsor: Capital Medical University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study tests whether infusing a cold magnesium sulfate solution directly into the brain during emergency clot removal can improve outcomes for people with acute ischemic stroke. About 42 adults aged 18-80 with severe strokes will be randomly assigned to receive either standard clot removal alone or clot removal plus the cold infusion. The main goal is to see if the treatment is safe and helps more people regain independence within 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: magnesium sulfate
What this could lead to: If it works, this could point toward a new way to protect the brain during stroke treatment, potentially reducing long-term disability.
What could go wrong: This is an early phase 1/2 trial with only 42 people, so results may not apply broadly. The infusion could cause side effects like heart rhythm changes or low body temperature.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE ISCHEMIC STROKE

Contacts and locations

Locations

Affiliated Hospital of Xuzhou Medical University

Xuzhou, Jiangsu, 221000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.