Stroke drug could help hours later with MRI guidance
NCT ID NCT07540416
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the clot-busting drug tenecteplase can improve recovery in people with acute ischemic stroke when given 4.5 to 9 hours after symptoms start. It uses a special MRI pattern (DWI-FLAIR mismatch) to identify patients who might still benefit. About 564 adults will be randomly assigned to receive either tenecteplase or a placebo, and their functional outcomes will be measured at 90 days.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan
Zhengzhou, Henan, 450052, China
Contact Phone: •••-•••-•••• Email: •••••@•••••