Stroke drug could help hours later with MRI guidance
NCT ID NCT07540416
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the clot-busting drug tenecteplase can improve recovery in people with acute ischemic stroke when given 4.5 to 9 hours after symptoms start. It uses a special MRI pattern (DWI-FLAIR mismatch) to identify patients who might still benefit. About 564 adults will be randomly assigned to receive either tenecteplase or a placebo, and their functional outcomes will be measured at 90 days.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan
Zhengzhou, Henan, 450052, China
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