Could J147 help stroke patients recover better?
NCT ID NCT07430917
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether the drug J147, given by IV after clot removal, helps people recover from an acute ischemic stroke. About 196 participants will receive either J147 or a placebo. Researchers will measure brain function and safety through MRI scans and blood tests over 90 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- J147 (a drug given by IV injection)
- What this could lead to
- If it works, this could point toward a new treatment to improve recovery after a stroke.
- What could go wrong
- This is an early phase 2 trial with only 196 participants, so results may not apply to everyone. The drug may not improve outcomes or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Dell Seton Medical Center at the University of Texas at Austin
Austin, Texas, 78712, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could muscle loss predict stroke recovery?
- Can a drug boost brain recovery after stroke?
- Can a blood Clot's inflammation predict stroke recovery?
- Can a new infusion drug boost stroke recovery?
- Can removing clots from tiny brain arteries boost stroke recovery?
- Could vague stroke symptoms delay lifesaving treatment?