Could J147 help stroke patients recover better?
NCT ID NCT07430917
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether the drug J147, given by IV after clot removal, helps people recover from an acute ischemic stroke. About 196 participants will receive either J147 or a placebo. Researchers will measure brain function and safety through MRI scans and blood tests over 90 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
J147 (a drug given by IV injection)
What this could lead to
If it works, this could point toward a new treatment to improve recovery after a stroke.
What could go wrong
This is an early phase 2 trial with only 196 participants, so results may not apply to everyone. The drug may not improve outcomes or could cause side effects.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- THUNDER Stroke Study: Penumbra System with Thund NCT05437055
- Stroke Alarm Efficacy Trial (NCT06315192)
- IMPROVE-II: FAST Model for Stroke Reperfusion (NCT06330051)
- Virtual Reality Rehab for Stroke Recovery - NCT07674329
- Endovascular Therapy for Basilar Artery Stroke (NCT07672795)
- Oropharyngeal Suction Tube for Stroke Pneumonia NCT07647666
Contacts and locations
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Study contacts
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Locations
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Dell Seton Medical Center at the University of Texas at Austin
Austin, Texas, 78712, United States
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