New hope for mild stroke: Clot-Buster may help when time is lost

NCT ID NCT07476898

Not yet recruiting Disease control Sponsor: First Hospital of China Medical University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a clot-dissolving drug called tenecteplase works better than standard antiplatelet pills for people who have a mild but disabling stroke caused by a large blocked artery. About 864 adults who arrive at the hospital 4.5 to 24 hours after symptoms start will be randomly assigned to receive either the drug or dual antiplatelet therapy. The main goal is to see if more patients recover with little or no disability after 90 days.

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Conditions

The condition(s) this trial relates to.

ischemic stroke large artery stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STROKE

Contacts and locations

Locations

Anshan Central Hospital

Anshan, Liaoning, 114001, China
Anshan Changda Hospital

Anshan, Liaoning, 114005, China
Benxi Central Hospital

Benxi, Liaoning, 117000, China
Central Hospital Affiliated to Shenyang Medical College

Shenyang, Liaoning, 110024, China
Chaoyang Central Hospital

Chaoyang, Liaoning, 122000, China
Dalian Municipal Central Hospital Affiliated of Dalian University of Technology

Dalian, Liaoning, 116033, China
Dandong Central Hospital

Dandong, Liaoning, 118000, China
Dandong First Hospital

Dandong, Liaoning, 118000, China
Fujian Medical University Union Hospital

Fuzhou, Fujian, 350001, China
Fushun Central Hospital

Fushun, Liaoning, 113006, China
Fuxin People's Hospital

Fuxin, Liaoning, 123000, China
Huludao Central Hospital

Huludao, Liaoning, 125000, China
Liaojian Group Fukuang General Hospital

Fushun, Liaoning, 113008, China
Liaojian Group Tieling Coal General Hospital

Tieling, Liaoning, 112700, China
Liaoning Provincial People's Hospital

Shenyang, Liaoning, 110016, China
Liaoyang Central Hospital

Liaoyang, Liaoning, 111000, China
Panjin Central Hospital

Panjin, Liaoning, 124010, China
Shenyang Fifth People's Hospital

Shenyang, Liaoning, 110023, China
Shenyang First People's Hospital

Shenyang, Liaoning, 110041, China
Shenyang Fourth People's Hospital

Shenyang, Liaoning, 110031, China
Shenyang Tenth People's Hospital

Shenyang, Liaoning, 110044, China
Sujiatun District Central Hospital

Shenyang, Liaoning, 110101, China
The First Affiliated Hospital of Jinzhou Medical University

Jinzhou, Liaoning, 121001, China
The Fourth Affiliated Hospital of China Medical University

Shenyang, Liaoning, 110032, China
The Second Affiliated Hospital of Shenyang Medical College

Shenyang, Liaoning, 110002, China
Tieling Central Hospital

Tieling, Liaoning, 112000, China
Tieling County Central Hospital

Tieling, Liaoning, 112600, China
Wafangdian Central Hospital

Wafangdian, Liaoning, 116300, China
Wafangdian Third People's Hospital

Wafangdian, Liaoning, 116300, China
Yingkou Central Hospital

Yingkou, Liaoning, 115000, China

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