Could your electrolytes predict kidney damage after a stroke procedure?
NCT ID NCT07546448
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study examines whether blood electrolyte levels are linked to kidney damage in people who have a stroke and undergo a clot-removal procedure. Researchers will review medical records from 250 patients treated between 2018 and 2026. The goal is to identify risk factors that could help prevent kidney injury after contrast dye is used.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors identify stroke patients at higher risk for kidney damage after a clot-removal procedure, allowing for closer monitoring or preventive steps.
- What could go wrong
- This is an observational study, not a treatment trial. It only looks at past data, so it cannot prove cause and effect. Results may not apply to all patients or lead to immediate changes in care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 250 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Apr 2026
An estimate. Start dates often move.
- Expected to finish
-
May 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This study includes adult patients (≥18 years) with acute ischemic stroke who underwent endovascular therapy at a tertiary referral center between 2018 and 2026. Patients with sufficient clinical and laboratory data, including pre- and post-procedural serum creatinine measurements, will be eligible for inclusion. The cohort reflects a real-world population of patients undergoing EVT, encompassing a wide range of demographic and clinical characteristics, including common vascular comorbidities. Patients will be stratified according to the development of contrast-induced acute kidney injury (CI-AKI) for comparative analyses.
- Ages
-
18 to 100 years
- Sex
-
Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years or older * Patients diagnosed with acute ischemic stroke * Patients who underwent endovascular therapy for acute ischemic stroke between 2018 and 2026 * Patients with a baseline NIHSS score of 6 or higher * Patients who received iodinated contrast medium during the endovascular procedure * Patients managed under general anesthesia * Patients with available pre-procedural and post-procedural serum creatinine measurements sufficient to assess contrast-induced acute kidney injury Exclusion Criteria: * Age younger than 18 years * Pre-existing acute kidney injury or chronic kidney disease meeting KDIGO stage 1-3 before endovascular therapy * APACHE score greater than 25 at the time of the procedure * Known allergy or hypersensitivity to iodinated contrast media * Exposure to iodinated contrast media within the previous 2 weeks * Use of nephrotoxic medications within the previous 2 weeks * History of myocardial infarction or previous stroke * Use of vasopressor/inotropic agents such as dopamine at the time of the procedure * Systemic steroid use at the time of the procedure * Incomplete medical records or missing laboratory data required for evaluation of CI-AKI
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Acute ischemic stroke are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Fatma Acil
Diyarbakır, Outside of the US, 21070, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Glenzocimab in anterior stroke with large ischemic core eligible for endovascular therapy
- Can a blood filter strip away toxins in septic shock?
- A simple protein test might flag kidney danger after heart surgery
- After stroke, a balloon or a stent? trial tests which rescue opens blocked brain arteries better
- Can a stroke drug shrink brain damage after clot removal?
- Can better nurse training reduce ICU complications?