Obstructive sleep apnea syndrome

This study tested whether adding a telerehabilitation program (using a mobile app, video calls, and online coaching) to standard CPAP therapy helps obese adults with severe sleep apnea. 180 participants were followed for 6 months to see if the program improved daytime sleepiness,…

This completed study tested a remote, self-guided lifestyle program for 696 veterans with obesity and obstructive sleep apnea. Participants watched videos, completed handouts, and tracked their eating and activity, with optional coaching. The goal was to see if this low-cost appr…

This large Phase 3 trial tested a once-weekly injection called retatrutide in over 2,300 adults with obesity or overweight who do not have type 2 diabetes. The study also looked at how the drug affects knee osteoarthritis and obstructive sleep apnea. Participants received either …

This study tested the Inspire system, a device that stimulates a nerve in the neck to keep the airway open during sleep. It involved 44 adults in Singapore with moderate-to-severe obstructive sleep apnea who could not use CPAP. The main goal was to confirm the device works proper…

This study tested whether getting a sleep doctor appointment within one month helps people with obstructive sleep apnea use their CPAP machine more regularly. About 100 adults participated. The goal was to see if faster care leads to better treatment adherence and improved sleepi…

This study looked at whether a diabetes drug called empagliflozin, combined with a breathing machine (CPAP), can improve sleep and heart function in 70 adults with both heart failure and obstructive sleep apnea. Participants were randomly assigned to take empagliflozin or not, an…

This completed phase 4 trial tested three different drug combinations to treat obstructive sleep apnea in 45 adults. The drugs aim to improve how the airway stays open during sleep. Participants took either a drug combo or a placebo before bed, and their sleep was monitored overn…

This completed trial tested whether a low-level laser device (Alesis OSA-1) can reduce breathing pauses in adults with obstructive sleep apnea. 35 participants received six 12-minute light treatments over three weeks. Researchers measured apnea events before and after treatment, …

This study looked at whether weight-loss surgery (sleeve gastrectomy) is better than diet and medication for adults aged 65 and older with severe obesity and related health problems like type 2 diabetes, high blood pressure, sleep apnea, and knee arthritis. Sixty patients chose e…

This study tested whether managing sleep apnea remotely with a breathing device (APAP) can lower blood pressure as well as traditional in-person care. Researchers enrolled 344 adults with suspected sleep apnea in Beijing. Participants were randomly assigned to either telemedicine…

This study looked at whether using a CPAP machine at night can reduce episodes of atrial fibrillation (a type of irregular heartbeat) in people who also have obstructive sleep apnea. Twenty-five adults with both conditions were enrolled. Half used CPAP while the other half were o…

This phase 2 trial tested a drug called lorundrostat in 48 adults with moderate-to-severe obstructive sleep apnea and high blood pressure. Participants took either the drug or a placebo for four weeks to see if it improved breathing during sleep and lowered blood pressure. The st…

This study looked at 19 people with sleep apnea and mild high blood pressure. It compared a drug called bosentan to the standard CPAP machine to see if the drug could lower blood pressure just as well. The goal was to find a simpler way to manage heart risks in sleep apnea patien…

This study looked at whether using a CPAP machine to treat sleep apnea soon after a stroke can improve heart health. 71 people with acute stroke and moderate-to-severe sleep apnea were randomly assigned to CPAP or usual care. Researchers measured changes in heart structure and bl…

This study tested whether acetazolamide, a cheap and well-tolerated water pill, can reduce sleep apnea severity and lower blood pressure in young adults (18–50 years old) who cannot or will not use a CPAP mask. 54 participants received either the drug or a placebo for two weeks e…

This study tested whether a special oral appliance called myTAP, combined with a mouth shield and deep dental cleaning, can reduce gum disease in people who snore and breathe through their mouth. 43 adults with mild to moderate gum disease completed the 12-week trial. The device …

This study tested a personalized surgical approach for children with obstructive sleep apnea who have small tonsils or Down syndrome. Instead of the standard tonsil and adenoid removal, doctors used a sleep endoscopy to see exactly where the airway collapses and chose surgeries b…

This study tested two doses (250 mg and 500 mg daily) of acetazolamide, a drug usually used for altitude sickness, in 91 adults with moderate to severe obstructive sleep apnea. The goal was to see if the drug could reduce breathing pauses during sleep by improving breathing contr…

This study tested a personalized treatment plan called VitalCare for people with obstructive sleep apnea who were starting CPAP therapy. The plan included remote monitoring and tailored follow-up to help patients use their CPAP machine more regularly. Researchers enrolled 113 par…

This study looked at whether monitoring oxygen levels at home for 14 nights gives a more accurate diagnosis of obstructive sleep apnea than the standard single-night test in a hospital. Researchers enrolled 130 adults with suspected sleep apnea. They compared results from home mo…

This study tested a wearable device called SUNRISE to see if it can accurately screen for obstructive sleep apnea in people with diabetes or chronic lung disease. Researchers compared its results to standard sleep testing in 37 adults. The goal is to make sleep apnea screening ea…

This study tested a wearable ring device (Belun Ring) to see if it can accurately screen for obstructive sleep apnea. 70 adults wore the ring during a standard overnight sleep test. The ring measures oxygen levels, pulse, and movement to estimate breathing disruptions. Researcher…

This study tested whether a Samsung Galaxy Watch can reliably detect moderate to severe obstructive sleep apnea (OSA) in adults. Researchers enrolled 152 people who were at high risk or already diagnosed with OSA. The watch's readings were compared to standard sleep tests to see …

This study tested whether a ring-shaped device worn on the finger can accurately diagnose obstructive sleep apnea compared to the standard overnight sleep lab test. 136 adults suspected of having sleep apnea wore the Belun Ring while also undergoing standard lab testing. The goal…

This study tested whether a special algorithm in a pacemaker can accurately diagnose sleep apnea in people with heart problems. Researchers compared the pacemaker's readings to a standard overnight sleep test in 66 participants. They also looked for a link between sleep apnea sev…

This study looked at whether a home sleep apnea test can accurately detect obstructive sleep apnea in children aged 5-12 who have already had their tonsils and adenoids removed. 62 children completed both a home test and an overnight in-lab sleep study. The goal was to see how we…

This study tested whether a smartphone app called Apneal can accurately diagnose sleep apnea. 491 adults wore the app on their chest during an overnight sleep test, and the app's results were compared to the standard hospital sleep test. The goal is to see if the app can reliably…

This study tested a combination of two drugs, atomoxetine and oxybutynin (called AtoOxy), as a potential pill-based treatment for obstructive sleep apnea (OSA). 117 adults with OSA who were not using CPAP took the medication for one month. The goal was to see if the drug combo co…

This study looked at whether extra family support helps children with Down syndrome and obstructive sleep apnea use their positive airway pressure (PAP) machine more regularly. 27 children aged 6-18 were split into two groups: one received standard care, the other got a family-in…

This study tested two simple treatments for snoring in people with mild sleep apnea: low-level laser therapy applied to the mouth and soft palate, and oropharyngeal exercises (like tongue and throat workouts). 180 adults aged 40-55 took part. The goal was to see which approach re…

This study tested whether a mild electrical current applied to the head (called transcranial electrostimulation, or TES) can help control pain after major sleep apnea surgery. 45 patients received TES along with standard care. The goal was to see if TES reduces pain and the need …

This study tested a 12-week remotely-supervised rehabilitation program for 60 men aged 25-65 with moderate to severe obstructive sleep apnea. The goal was to see if the program could improve breathing pauses during sleep, daytime sleepiness, and overall quality of life. Participa…

This study tested a six-session behavioral sleep program, called Apnea and Insomnia Relief (AIR), in 118 Gulf War veterans with Gulf War Illness. The program combined sleep education, motivation for using a breathing machine, and insomnia therapy, all done via telehealth. Researc…

This study looked at whether surgery to fix a blocked nose can improve snoring and sleep apnea in adults. Thirty people with nasal obstruction and sleep apnea had surgery. The main goal was to see if their breathing pauses during sleep (measured by the apnea-hypopnea index) got b…

This study tested whether a 14-day course of the sleep medication eszopiclone could help people with both insomnia and obstructive sleep apnea use their CPAP machine more consistently. Sixty participants were randomly assigned to receive either eszopiclone or a placebo. The resea…

This study tested whether using a CPAP machine (a device that helps you breathe during sleep) can also improve oral frailty (weakness in the mouth) and dysphagia (trouble swallowing) in people with obstructive sleep apnea. Researchers followed 450 adults aged 50 and older for six…

This study tested whether a mindfulness program could help teenagers with obstructive sleep apnea use their CPAP machine more regularly. 37 teens aged 13-18 with moderate to severe sleep apnea took part. The program taught skills like awareness and resilience, and the researchers…

This study tested whether a short course of the steroid dexamethasone can reduce the severity of obstructive sleep apnea in children aged 2 to 10. Ten children with moderate-to-severe sleep apnea received either the drug or a placebo for three days. The goal was to see if the ste…

This study tested a dietary supplement called Speed Sleep in 60 adults aged 18-65 who have trouble sleeping. Participants took either the supplement or a placebo daily for 4 weeks. Sleep quality and quantity were measured using Fitbit trackers and questionnaires.

This study tested whether sleeping in a semi-upright position (45-degree angle) after surgery could prevent sleep apnea from getting worse. 164 adults with sleep apnea who were having elective inpatient surgery took part. Half slept semi-upright and half slept flat on their backs…

This study looked at whether wearing compression stockings during the day for 28 days could reduce the number of breathing pauses (apneas) per hour in people with moderate to severe sleep apnea. The idea is that stockings prevent fluid from building up in the legs and moving to t…

This study tested a phone-based health coaching program to help people with sleep apnea use their positive airway pressure (PAP) device more often. 27 adults who were not using their device enough took part. The coaching aimed to improve device use and reduce daytime sleepiness.

This study tested whether wearing a smart watch and using a health app could help people with obstructive sleep apnea use their CPAP machine more regularly. 46 adults who either had never used CPAP or used it less than 4 hours a night were given a smart watch and app for 90 days.…

This completed study tested whether semaglutide, a drug used for type 2 diabetes and weight loss, could improve sleep apnea in 15 people with diabetes or obesity. Researchers measured breathing pauses during sleep (AHI) after 1 and 4 weeks of treatment. The goal was to see if the…

This study tested whether a dental mouthpiece (mandibular advancement device) can reduce frequent nighttime urination in adults with obstructive sleep apnea. Eleven participants who woke up to pee at least twice a night used the device and tracked their bathroom visits. The goal …

This study looked at whether sucking on ice (oral cryotherapy) can reduce sore throat and improve daily life in people with sleep apnea after robotic surgery. 64 adults took part. The goal was to see if this simple, low-cost method could ease pain and help patients get back to no…

This study tested a behavioral sleep treatment in 36 veterans who have PTSD, insomnia, and sleep apnea. The goal was to see if improving sleep also improves quality of life and daily functioning. Participants attended therapy sessions and reported their sleep and well-being throu…

This study tested whether a daily mix of plant protein and two herbs (ashwagandha and rhodiola) could improve sleep in 100 adults aged 35-70 with sleep troubles. Participants took either the supplement or a placebo for 30 days and reported their sleep quality daily. The goal was …

This study tested whether the drug acetazolamide can improve sleep-disordered breathing in 39 adults with chronic pain who use opioids. Participants took either the drug or a placebo for one week each. The goal was to see if the pill could reduce sleep apnea events as an alternat…

This study looked at whether giving a low dose of a muscle relaxant (rocuronium) during bronchoscopy—a procedure where a tube is inserted into the lungs—could reduce complications like throat spasms and coughing. 153 adults having elective bronchoscopy were split into two groups:…

This early study tested a product called Chenghuang Circadian Rhythm Regulator in 15 adults with ongoing sleep problems. The goal was to see if it could improve sleep quality and immune markers. Results are not yet reported, but the study was small and had no comparison group.

This study tested a new automatic setting (Auto-EPAP) on a ventilator to see if it could better manage airway blockages during sleep compared to the standard manual setting. It involved 23 adults with conditions like sleep apnea, COPD, or obesity-related breathing problems who al…

This study tested a drug called solriamfetol in 59 adults with obstructive sleep apnea who also had trouble thinking clearly and felt very sleepy during the day. The goal was to see if the drug could improve cognitive function, like attention and processing speed. Participants to…

This study tested whether a headband called Muse-S, which senses brain activity, could help midlife women with sleep problems like insomnia. Thirty-one women going through menopause wore the device at home. The goal was to see if it was practical and if it improved sleep quality …

This early study tested whether the drug acetazolamide can reduce breathing pauses during REM sleep in people with obstructive sleep apnea who cannot use a CPAP machine. Eleven participants took either the drug or a placebo for a few nights. Researchers measured breathing events …

This study tested whether giving children a single oral dose of steroid right after tonsillectomy can reduce pain and lower the need for strong painkillers. It involved 163 children aged 3 to 12 having outpatient tonsil surgery. Researchers measured pain scores and opioid use for…

This study tested whether orofacial myofunctional therapy (OMT) — simple tongue and throat exercises done during the day — can improve breathing during sleep in people with mild-to-moderate sleep apnea. 209 adults with sleep apnea participated, comparing OMT to a placebo exercise…

This study tested whether acupressure—a gentle finger-pressure technique on specific body points—could improve sleep in elderly people living in care homes. 75 residents took part, with half receiving 12 acupressure sessions over four weeks. The results showed that those who rece…

This study tested an online program called ALDER that teaches older adults skills to boost positive emotions and reduce anxiety. 33 people aged 65 and older who used benzodiazepines (anti-anxiety or sleep medications) at least twice a week took part. Over 5 weeks, they learned an…

This study tested a special educational program based on motivational interviewing to help people with sleep apnea use their CPAP machine more regularly. 100 adults newly prescribed CPAP took part. The program aimed to improve adherence, motivation, quality of life, and daytime s…

This study looked at 558 adults with mild to moderate sleep apnea who also don't get enough sleep. Researchers compared two programs: one focused on improving use of a PAP machine, and another on sleep education. The goal was to see which works better for reducing daytime sleepin…

This study tested whether a high-flow nasal cannula (HFNC) can reduce the risk of low oxygen levels during sedated gastrointestinal endoscopy in 80 adults with high-risk obstructive sleep apnea. Participants had a STOP-Bang score of 5 or higher and were undergoing gastroscopy, co…

This study tested whether a safe sleep aid could help people with obstructive sleep apnea use their CPAP machine more each night. Many patients struggle to keep the mask on all night, often because they wake up easily. The trial gave a medication to raise the sleepers' arousal th…

This study tested whether a jaw-widening surgery (surgically assisted maxillary expansion) could improve quality of life in 9 adults with obstructive sleep apnea. Participants completed sleep questionnaires before surgery and again 3 months and 1 year after. The goal was to see i…

This study tested a new combination pill called AD109 for obstructive sleep apnea (OSA) in 646 adults who could not tolerate CPAP machines. The pill aims to reduce breathing pauses during sleep by targeting brain chemicals. Results will show if it improves the apnea-hypopnea inde…

This study tested a new medication called AD109 (a combination of two drugs) to treat obstructive sleep apnea in adults who cannot or will not use a CPAP machine. About 660 participants took either the pill or a placebo for one year. The main goal was to see if the pill reduces t…

This study tested whether doing special tongue and throat exercises for 12 weeks after surgery helps people with moderate-to-severe sleep apnea breathe better at night. 51 adults were split into two groups: one did the exercises after surgery, the other had surgery only. The exer…

This study tested a behavioral program to help older veterans with obstructive sleep apnea use their positive airway pressure (PAP) machine more consistently. About 100 veterans who had stopped using their PAP device worked with a sleep coach over several sessions. The goal was t…

This study tested a special water bottle nozzle designed to strengthen mouth and tongue muscles while you drink. 43 adults with mild to moderate sleep apnea used the nozzle daily for 8 weeks. Researchers measured changes in sleep quality, snoring, and apnea severity to see if thi…

This study tested a new CPAP mask (the Eclipse) against a traditional mask in 70 adults with obstructive sleep apnea. Participants tried each mask three times and reported how much they liked it and any technical issues. The goal was to see if the new design is easier and more pl…

This study tested how easy a new CPAP mask (the Eclipse) is to use compared to a traditional mask. 35 adults with sleep apnea tried both masks three times each. Researchers measured setup time, technical issues, and how often help was needed.

This study tested a new CPAP mask called DreamPort-Eclipse against a traditional nasal mask in 173 adults with obstructive sleep apnea. Participants used the mask for 6 hours a night over 60 days. The goal was to see if the new mask reduces air leaks, improves breathing scores, a…

This study tested a sleep and circadian treatment (TranS-C) for people with severe mental illness (SMI) in community mental health centers. The treatment was adapted to better fit these settings. Researchers looked at whether it improved sleep, daily functioning, and symptoms in …

This study tested whether adding the sleep medication eszopiclone (Lunesta) to brief behavioral therapy improves sleep quality and CPAP use in veterans with PTSD and complex insomnia. Fifty-three veterans who had trouble sticking with CPAP therapy for sleep apnea took part. The g…

This study tested two versions of a sleep treatment for people with severe mental illness in community mental health centers. One version was the standard treatment, and the other was adapted to better fit patients' needs. The goal was to see if training clinic staff to deliver t…

This study tested a group program for people with moderate-to-severe sleep apnea who were having trouble using their breathing machine (PAP). The program aimed to help them use the machine more often and for longer each night. Researchers compared the group program to usual care …

This study tested a home-based lifestyle program for people with severe obstructive sleep apnea and severe obesity. The program used a tablet and sensors to track sleep, diet, and exercise, along with regular calls from a health coach. The goal was to see if people could use the …

This study looked at ways to help people who had a stroke use a CPAP machine for sleep apnea during their rehab stay. Sleep apnea is common after stroke and can slow recovery. The researchers tested different approaches to improve how often patients used the CPAP machine over thr…

This study tested a steroid nasal spray (mometasone furoate) in 130 children aged 3-12 who snore and have sleep-disordered breathing. The goal was to see if the spray could relieve symptoms enough to avoid surgery to remove tonsils or adenoids. Children used the spray daily for 6…

This study tested a new nasal mask called the F&P Caramel for people with obstructive sleep apnea. 45 adults who already use a similar mask tried it at home for 14 days. Researchers measured how well the mask controlled breathing pauses (AHI score) and daytime sleepiness. The goa…

This study tested a new nasal pillows mask called F&P Toffee for people with obstructive sleep apnea. Forty adults who already use PAP therapy tried the mask at home for 14 days. Researchers measured how well the mask controlled breathing pauses (AHI score) and how sleepy partici…

This study tested whether a remote patient monitoring platform (MonitAir) could help people with obstructive sleep apnea use their CPAP machine more consistently. 200 adults starting CPAP therapy were randomly assigned to receive standard coaching or enhanced monitoring with the …

This small study tested whether the sleep medication lemborexant (Dayvigo) can help people with moderate-to-severe obstructive sleep apnea (OSA) who have a low arousal threshold—meaning they wake up easily during sleep. Ten untreated adults each took the drug or a placebo on two …

This study looks at a nerve in the neck called the ansa cervicalis, which controls muscles that help keep the airway open. Researchers will measure the nerve's size and shape in 50 adults having neck surgery for head and neck cancer. They will also test how stimulating the nerve …

This study investigates why people develop obstructive sleep apnea (OSA) and whether the underlying cause affects how they respond to different treatments. Researchers will test three approaches—CPAP, a sleep medication (eszopiclone), and supplemental oxygen—in adults with OSA. T…

This study looked at how sleep quality improves when people with obstructive sleep apnea start using a CPAP machine. Researchers used a special headband to track deep sleep at home for 7 nights before and 9 nights after starting treatment. The goal was to see how quickly sleep ge…

This early study tested whether a small electrode placed near the nerve that controls tongue movement could help people with obstructive sleep apnea. Fourteen adults who already needed surgery took part. The main goal was to see if the approach was safe and could make the tongue …

This study tested whether stimulating certain nerves or muscles in the throat can improve breathing in people with obstructive sleep apnea. Researchers placed temporary electrodes and measured airflow during sleep in 35 adults. The goal was to see if this approach is feasible and…

This early study tested whether a small electrode placed near the tongue nerve could be safely used in people with obstructive sleep apnea. 14 adults who could not use CPAP took part. The goal was simply to see if the nerve could be reached and stimulated, not yet to treat the co…

This study looked at the medical records of one person from a sleep clinic to see if their breathing problems were due to a condition called dysanapsis (where airways are smaller than normal) rather than true asthma. The goal was to better understand why some people with sleep ap…

This study looked at 103 adults with narcolepsy or obstructive sleep apnea to see if anxiety, social, or work factors affect their ability to stay awake during a standard test. Participants filled out an anxiety questionnaire before the test. The goal is to better understand why …

This study looked at 395 adults with obstructive sleep apnea to see if a new tool called the Baveno classification agrees with the standard sleep test (polysomnography) for deciding treatment. Researchers compared symptoms and health records against sleep lab results. The goal is…

This study tested a new approach called DREAM, where Veterans at risk for sleep apnea could go straight to home sleep testing without an initial in-person clinic visit. Over 6,500 Veterans took part to see if this speeds up diagnosis and treatment. The goal is to make sleep apnea…

This completed study looked at whether chemicals in the blood (metabolomics) can help diagnose obstructive sleep apnea and track changes with treatment. Researchers analyzed stored blood samples from 388 people with and without sleep apnea, and also collected new samples from pat…

This completed Phase 1 study looked at whether obstructive sleep apnea (OSA) might contribute to Alzheimer's disease. Researchers studied 182 older adults aged 65-85 with and without OSA, using brain scans and breathing tests. The goal was to understand how sleep disruptions like…

This completed study looked at how sleep apnea and other health problems like diabetes and high blood pressure affect pain after root canal treatment. 78 adults were divided into three groups: those with sleep apnea, those with diabetes or high blood pressure, and healthy people.…

This study looked at whether a wearable device (Xiaomi Mi Band 8) can accurately detect sleep-related breathing disorders. About 300 adults wore the band during a standard overnight sleep test. Researchers compared the band's sleep-stage data with the hospital test to see if wear…

This study looked at 77 never-smokers newly diagnosed with lung cancer to see how many also have sleep apnea and whether sleep apnea affects their cancer outlook. Participants had a sleep test before starting cancer treatment. The goal is to understand if sleep apnea is a hidden …

This completed study tested two different PAP systems (machines, masks, and tubing) for obstructive sleep apnea. Thirty employees of the device maker used each system for a week and rated their experience. The goal was to gather feedback to guide future product improvements, not …

This study followed 520 French adults with central or mixed sleep apnea to see how a treatment called adaptive servo-ventilation (ASV) improved their sleep quality. Participants used a breathing device that adjusts pressure in real time. The goal was to measure changes in sleep q…

This study looked at 89 obese pregnant women to find out how common sleep apnea is and whether it is linked to high blood pressure, preeclampsia, or poor fetal outcomes. Participants had a sleep test (polysomnography) to detect apnea. The goal was to understand the connection and…

This study tested a computer system designed to help doctors more accurately diagnose and manage complex brain disorders like dementia, epilepsy, and sleep problems. Researchers collected health data from 635 people visiting specialty clinics, including healthy volunteers, to see…

This study looked at how having fibromyalgia changes body measurements and sleep patterns in people with obstructive sleep apnea. Researchers measured neck, waist, and hip sizes, and used sleep tests and ultrasound to compare 77 participants. The goal was to better understand the…

This study looked at whether treating obstructive sleep apnea (OSA) can also reduce pain and problems in the jaw and face, known as temporomandibular disorders (TMD). Forty-one adults with OSA but not yet on treatment were checked for TMD before starting therapy and again after a…

This completed study tested two different methods for positioning a dental sleep appliance used to treat obstructive sleep apnea. Eleven adults each tried both a standard forward-jaw technique and a technique based on saying certain sounds. The goal was to see if the speech-based…

This study looked at 106 people with obesity who were scheduled for weight-loss surgery. Researchers measured how their upper airways behaved during sleep and used MRI scans to see if changes after surgery could explain why some develop obstructive sleep apnea and others do not. …

This study looked at whether a special camera test done during sleep (called drug-induced sleep endoscopy) can help doctors choose the right non-CPAP treatment for people with obstructive sleep apnea. 35 adults who could not use CPAP took part. The goal was to see if this approac…

This completed pilot study looked at whether a quick, non-invasive eye scan (OCT angiography) can detect early blood vessel changes in the retina of people with obstructive sleep apnea. Researchers compared 166 adults with and without sleep apnea. The goal was to see if retinal i…

This study looked at how low oxygen levels (hypoxia) in people with obstructive sleep apnea affect the body's ability to use insulin. Researchers measured insulin resistance in the liver and fat tissue of 48 non-diabetic adults. The goal was to understand why some sleep apnea pat…

This study looked at 150 children and adults who had their tonsils removed using one of three surgical methods: BiZact, coblation, or bipolar. Researchers measured pain after surgery, how long the operation took, when patients could eat solid food again, and how much the devices …

This study looked at how well the diaphragm works in people with obstructive sleep apnea (OSA). Researchers used ultrasound to measure diaphragm movement in 60 adults with OSA. The goal was to see if diaphragm function is linked to how severe the sleep apnea is.

This completed study tracked 132 children with obstructive sleep apnea who had their tonsils removed. Researchers recorded how many had breathing problems after surgery, especially those with other health issues. The goal was to create a simple flowchart to help doctors decide wh…

This completed study looked at how consistently 300 obese adults (BMI over 30) used positive airway pressure therapy for sleep-disordered breathing. Researchers tracked whether patients used the device at least 4 hours per night for 70% of nights within the first 90 days and agai…

This study looked at 40 adults who had a blood clot in their lungs (pulmonary embolism). Researchers compared those who also had sleep-disordered breathing (like sleep apnea) with those who did not. The goal was to see if sleep problems affect short-term recovery and the chance o…

This study looked at how well smartphone apps and a special ring (Belun Ring) can measure sleep quality in adults getting braces or other orthodontic treatment. 52 people from Case Western Reserve University's dental clinic took part. They answered sleep questionnaires and used t…

This study looked at how specific tongue muscles help keep the airway open during sleep in people with obstructive sleep apnea. Researchers used a special camera during sleep-like sedation to measure airway collapse. The goal was to understand the mechanisms behind airway obstruc…

This completed study with 40 participants explored factors that might predict obstructive sleep apnea in people with Down syndrome. Researchers used a range of assessments, including sleep studies, heart monitoring, and exercise tests, to identify early warning signs. The goal is…

This study looked at how sleep quality, when people eat, and gut bacteria are linked to obesity. Researchers tested a mobile app to help people make healthier lifestyle changes. The study included 133 adults with different body weights, including some with sleep apnea. The goal w…

This study looked at whether a nutrition and behavior change program could help reduce sleep apnea in people who are overweight or obese. About 400 adults took part, and researchers measured changes in sleep apnea risk, daytime sleepiness, and weight loss. The goal was to see if …

This completed study looked at 825 adults with type 1 diabetes who use an insulin pump to see how many also have obstructive sleep apnea. Researchers used overnight oxygen tests and sleep studies to find cases. The goal was to understand if sleep apnea is linked to diabetes compl…

This study followed over 200 sleep apnea patients from a large European database to see how many developed heart problems, metabolic issues, cancer, or died over time. Researchers also checked whether using CPAP therapy (a common sleep apnea treatment) affected these risks. The g…

This study looked at how two drugs, atomoxetine and oxybutynin, affect throat muscles in people with obstructive sleep apnea (OSA). The goal was to understand why the combination works better than either drug alone. 27 adults with OSA took part, and researchers measured muscle ac…

This study looked at 209 adults with moderate to severe sleep apnea to better understand how the condition affects the body. Instead of just counting breathing pauses, researchers used special measures like oxygen drops, heart rate changes, and sleep disruption. Participants used…

This study follows 202 people who were first checked for sleep apnea as children in 2003. Researchers want to see how their sleep apnea changed over 18 years and whether it is linked to heart problems or thinking difficulties. Participants will repeat sleep tests, blood pressure …

This study tested whether a thin, flexible tube with pressure sensors (high-resolution manometry) can pinpoint where the airway gets blocked during sleep in people with obstructive sleep apnea. 18 adults and children underwent both the standard scope test and the new tube method.…

This study looked at how sleep apnea might make brain problems worse after surgery. Researchers enrolled 32 adults with moderate-to-severe sleep apnea who were scheduled for surgery. They used brain scans and memory tests before surgery, two days after, and six months later to tr…

This study looked at how often children's oxygen levels drop after surgery for sleep apnea. 178 children who had their tonsils and adenoids removed were monitored with a continuous pulse oximeter. The goal was to better understand oxygen desaturation patterns in the hospital afte…

This study looked at how a mix of home and on-site resistance training affects muscle loss and fatigue in people with chronic respiratory diseases like COPD, obstructive sleep apnea, or lingering COVID-19 symptoms. 72 adults aged 30-85 completed 18 exercise sessions. Researchers …

This study looked at 28 people with both stable coronary artery disease and moderate sleep apnea. Researchers measured blood markers of oxidative stress (a type of cell damage) before and after 3 months of CPAP therapy. The goal was to see if CPAP could reduce oxidative stress, w…

This completed study observed 563 patients who had weight-loss (bariatric) surgery and received extra oxygen during their first night in the hospital. Researchers tracked how often oxygen levels fell below 90% and what actions nurses took, like adjusting the oxygen flow or reposi…

This study looked at how sleep apnea and low oxygen levels affect muscle strength and breathing in people with chronic spinal cord injury. Thirty adults with neck-level spinal cord injuries were tested using hand grip strength and muscle activity measurements. The goal was to und…

This study looked at 172 adults with obstructive sleep apnea to compare the risk of heart attacks, strokes, and eye problems between two common treatments: a CPAP machine and a dental mouthpiece. Researchers did not give any new treatment—they simply observed patients already usi…

This study looked at how moving an oral appliance forward by just one millimeter at a time affects sleep apnea severity and symptoms like daytime sleepiness. Twenty adults with moderate or severe sleep apnea took part. Researchers measured breathing pauses during sleep and used q…

This study followed 60 people who survived a severe breathing crisis in the ICU. Researchers wanted to learn about their health, sleep disorders, and why some need to return to the hospital. Participants had sleep tests three months after leaving the ICU and were tracked for a ye…

This study looked at how people with obstructive sleep apnea and their bed partners adapt to CPAP therapy, a common treatment that uses a machine to keep airways open during sleep. Researchers interviewed 24 patients and their partners to understand what helps or hinders consiste…