Blood markers may reveal sleep apnea and treatment success

NCT ID NCT04572269

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at whether chemicals in the blood (metabolomics) can help diagnose obstructive sleep apnea and track changes with treatment. Researchers analyzed stored blood samples from 388 people with and without sleep apnea, and also collected new samples from patients using CPAP therapy. The goal was to find a blood-based signature that correlates with sleep apnea severity and treatment adherence.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test to diagnose sleep apnea and monitor how well treatment is working.

What could go wrong

This is an observational study using existing samples and real-world data, so results may not be definitive. It does not test a new treatment or intervention.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Iceland

    Reykjavik, 108, Iceland

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States