Better sleep could ease severe mental illness symptoms, study finds

NCT ID NCT04154631

Completed Symptom relief Sponsor: University of California, Berkeley Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a sleep and circadian treatment (TranS-C) for people with severe mental illness (SMI) in community mental health centers. The treatment was adapted to better fit these settings. Researchers looked at whether it improved sleep, daily functioning, and symptoms in 489 participants. The goal was to see if the adapted version works better than the standard one and if it's acceptable to providers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Behavioral sleep and circadian treatment (TranS-C)
What this could lead to: If successful, this could provide an effective, practical sleep treatment tailored for people with severe mental illness in community settings, improving daily functioning and well-being.
What could go wrong: This is an implementation study, not a test of a new drug or cure. The treatment is behavioral, so results depend on provider and patient engagement, and may not work for everyone.

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Conditions

The condition(s) this trial relates to.

Chronobiology Disorders circadian rhythm sleep disorder sleep disorder sleep-wake disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CIRCADIAN DYSREGULATION SLEEP DISORDER

Contacts and locations

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Locations

Alameda County Behavioral Health Care Services

Oakland, California, 94606, United States
Bay Area Community Health

San Jose, California, 95148, United States
Contra Costa Health, Housing, and Homeless Services Division

Concord, California, 94520, United States
County of Santa Cruz Behavioral Health Services for Children and Adults

Santa Cruz, California, 95060, United States
Kings County Behavioral Health

Hanford, California, 93230, United States
Lake County Behavioral Health Services

Lucerne, California, 95458, United States
Monterey County Behavioral Health

Salinas, California, 93906, United States
Placer County Health and Human Services, Adult System of Care

Roseville, California, 95678, United States
Santa Barbara County Department of Behavioral Wellness

Goleta, California, 93110, United States
Solano County Department of Health & Social Services, Behavioral Health Services

Fairfield, California, 94533, United States

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