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Snoring kids may skip surgery: nasal spray trial shows promise

NCT ID NCT05382494

Completed Symptom relief Sponsor: Murdoch Childrens Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a steroid nasal spray (mometasone furoate) in 130 children aged 3-12 who snore and have sleep-disordered breathing. The goal was to see if the spray could relieve symptoms enough to avoid surgery to remove tonsils or adenoids. Children used the spray daily for 6 weeks, and their symptoms were tracked using a parent questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Mometasone Furoate nasal spray
What this could lead to
If it works, this nasal spray could offer a non-surgical option for children with snoring and sleep-disordered breathing, potentially reducing the need for tonsil or adenoid removal.
What could go wrong
This is a small, completed Phase 4 trial. The steroid spray may not work better than saline, and long-term effects in children are not fully known. Results may not apply to all kids.

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Conditions

The condition(s) this trial relates to.

adenoid hypertrophy obstructive sleep apnea syndrome sleep apnea syndrome sleep disorder sleep-wake disorder Snoring

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADENOIDAL DISORDER OBSTRUCTIVE SLEEP APNEA OF CHILD SLEEP DISORDER; BREATHING-RELATED SLEEP DISORDERS IN CHILDREN SNORING TONSILLAR HYPERTROPHY

Contacts and locations

Locations

  • Monash Children's Hospital

    Clayton, Victoria, 3168, Australia

  • Royal Children's Hospital / Murdoch Children's Research Institute

    Parkville, Victoria, 3052, Australia

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