Tailored surgery may help kids with sleep apnea who have small tonsils or down syndrome

NCT ID NCT05154214

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a personalized surgical approach for children with obstructive sleep apnea who have small tonsils or Down syndrome. Instead of the standard tonsil and adenoid removal, doctors used a sleep endoscopy to see exactly where the airway collapses and chose surgeries based on that. The study enrolled 30 children aged 2 to 18 and measured quality of life and sleep apnea severity changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Adenotonsillectomy (removal of tonsils and adenoids) and drug-induced sleep endoscopy directed surgery

What this could lead to

If successful, this personalized surgical approach could improve sleep apnea outcomes in children with small tonsils or Down syndrome and reduce unnecessary surgeries.

What could go wrong

This is a small, completed feasibility study with only 30 participants, so results may not apply broadly. The personalized approach may not prove superior in larger trials.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Down syndrome obstructive sleep apnea syndrome sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States