Tailored surgery may help kids with sleep apnea who have small tonsils or down syndrome

NCT ID NCT05154214

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a personalized surgical approach for children with obstructive sleep apnea who have small tonsils or Down syndrome. Instead of the standard tonsil and adenoid removal, doctors used a sleep endoscopy to see exactly where the airway collapses and chose surgeries based on that. The study enrolled 30 children aged 2 to 18 and measured quality of life and sleep apnea severity changes.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Adenotonsillectomy (removal of tonsils and adenoids) and drug-induced sleep endoscopy directed surgery
What this could lead to
If successful, this personalized surgical approach could improve sleep apnea outcomes in children with small tonsils or Down syndrome and reduce unnecessary surgeries.
What could go wrong
This is a small, completed feasibility study with only 30 participants, so results may not apply broadly. The personalized approach may not prove superior in larger trials.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

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