Small study tests tiny adjustments to sleep apnea device

NCT ID NCT05056766

Completed Knowledge-focused Sponsor: Centre Hospitalier de Valence Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at how moving an oral appliance forward by just one millimeter at a time affects sleep apnea severity and symptoms like daytime sleepiness. Twenty adults with moderate or severe sleep apnea took part. Researchers measured breathing pauses during sleep and used questionnaires to track fatigue and sleepiness, without knowing the results until the end.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: oral appliance advancement (titration)
What this could lead to: If successful, this could help doctors fine-tune oral appliance settings for sleep apnea patients, improving symptom relief.
What could go wrong: This is a small, observational study with only 20 participants, so results may not apply to everyone. It does not test a new treatment, only how to adjust an existing one.

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Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome respiratory system disorder sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RESPIRATORY TRACT DISEASES SLEEP APNEA SYNDROMES SLEEP APNEA, OBSTRUCTIVE

Contacts and locations

Locations

CH Valence

Valence, 26953, France

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