Freezing away sleep apnea: a new procedure targets throat fat to open the airway

NCT ID NCT07720219

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This trial tests a cryotherapy procedure that freezes and destroys excess fat in the upper airway to reduce airway collapse during sleep. It enrolls adults with moderate-to-severe obstructive sleep apnea who cannot use standard treatments like CPAP. The study measures whether the treatment lowers apnea-hypopnea index scores and oxygen desaturation events at six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a cryotherapy procedure that freezes and destroys excess fat in the upper airway to reduce airway collapse during sleep
What this could lead to
If it works, this could offer a one-time, non-surgical option for people with obstructive sleep apnea who cannot tolerate CPAP machines or mouthpieces.
What could go wrong
This is an early study focused on safety and effectiveness at six months. The procedure may cause side effects like swelling or pain, and not everyone may see enough improvement.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

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