Could a 66-cent pill replace CPAP for sleep apnea?

NCT ID NCT05616260

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether acetazolamide, a cheap and well-tolerated water pill, can reduce sleep apnea severity and lower blood pressure in young adults (18–50 years old) who cannot or will not use a CPAP mask. 54 participants received either the drug or a placebo for two weeks each. The goal is to offer a simple, once-daily pill option for the millions of OSA patients who struggle with current treatments.

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Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UC San Diego; Altman Clinical and Translational Research Institute Building

    La Jolla, California, 92121, United States