Obstructive sleep apnea syndrome

This study looked at whether using a positive airway pressure (PAP) machine at night can reduce the return of atrial fibrillation (an irregular heartbeat) in people who also have obstructive sleep apnea. About 129 participants with both conditions were assigned to receive either …

This study compared a new prototype nasal mask (Whitsundays) to a standard mask (AirFit N30i) in 30 adults with obstructive sleep apnea. Participants used each mask for 7 nights at home. The goal was to see which mask sealed better, was more comfortable, and easier to use. The st…

This study compared two types of non-invasive breathing support for people with sudden breathing failure who are obese or have sleep apnea. One machine automatically adjusts pressure and volume, while the other uses a fixed pressure setting. The goal was to see which method clear…

This study tested a single dose of danavorexton in 41 people with moderate to severe sleep apnea who were having abdominal surgery. The goal was to see if the drug could help them breathe steadily in the recovery room. The trial was terminated early, so results are incomplete.

This study looked at whether using a CPAP machine at night could reduce abnormal acid reflux and lung inflammation in people with idiopathic pulmonary fibrosis (IPF) who also have sleep apnea. Only 7 people enrolled before the study was terminated early. The goal was to measure c…

This study aimed to find early signs of heart and blood vessel damage in people with obstructive sleep apnea, before serious symptoms appear. Researchers planned to follow 133 patients and check if CPAP treatment could reverse these early changes. The study was terminated early, …

This study involved 65 adults with obstructive sleep apnea who had been using CPAP therapy for at least 6 months. Participants stopped using CPAP for 2 weeks so researchers could measure changes in blood vessel function and nerve control of the heart. The goal was to see if a spe…