Nyu Langone Health

This study looks at whether the shingles vaccine is safe and works well for people with lupus. About 224 adults with lupus will receive either the vaccine or a placebo, and researchers will track lupus flare-ups and immune response for 24 weeks. The goal is to see if the vaccine …

This early-stage study tests a drug called CpG 1018 that aims to stimulate the immune system in people with mild cognitive impairment or mild Alzheimer's dementia. The main goal is to check the drug's safety and tolerability at three different dose levels. The study involves 39 p…

This study tests a new drug called DRP-104 in people with advanced non-small cell lung cancer that has specific genetic changes (NFE2L2 or KEAP1). The drug works by blocking glutamine, a nutrient cancer cells need to grow. About 37 participants will receive the drug to see if it …

This study tests whether remote exercise programs (using a smartphone app or live video classes) can help adults over 45 who are at risk for heart disease become more active. Thirty participants will be randomly assigned to one of four exercise groups for 12 weeks. The goal is to…

This study looks at whether people aged 60 and older with stable lupus can safely stop taking hydroxychloroquine, a drug that can harm the eyes over time. About 330 participants will either continue the drug or receive a placebo for one year. The goal is to see if stopping the dr…

This early-phase study tests a new drug called XRD-0394 combined with radiation therapy for people with high-grade gliomas, a fast-growing brain cancer. The main goal is to find a safe dose and check for side effects. About 39 adults with newly diagnosed or returning tumors will …

This study tests if e-cigarettes can help people with opioid use disorder cut down on smoking regular cigarettes. Researchers will compare e-cigarettes to standard nicotine patches and gum, along with counseling. The goal is to see which approach works better for reducing smoking…

This study tests whether adding financial coaching to standard smoking cessation counseling helps people with low income quit smoking more successfully. About 600 smokers in New York City who smoke at least 5 cigarettes daily and have low income will be randomly assigned to eithe…

This study tests whether giving people with serious mental illness either e-cigarettes or nicotine patches, along with counseling and text messages, helps them cut down on smoking. 60 adult smokers who want to reduce but not necessarily quit will be followed for 12 weeks. The goa…

This study tests whether using portable air cleaners at home can reduce indoor air pollution and help lower blood pressure. Researchers will enroll 440 adults with high blood pressure who live in New York City public housing and do not smoke. Participants will use air cleaners an…

This study looks at whether making it easier for people to get methadone to take at home (instead of going to a clinic every day) helps them stay in treatment for opioid use disorder. The researchers will work with 36 clinics to help them offer more take-home doses. About 318 adu…

This study compares two treatments for people with a serious but stable blood clot in the lungs (submassive pulmonary embolism). Half of the 500 participants will receive standard blood thinners alone, while the other half will also get a catheter procedure to remove the clot. Th…

This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) can help people with opioid addiction who still use illegal opioids despite being on methadone. About 240 participants will receive either a high, medium, or low dose of psilocybin and…

This study aims to prevent permanent heart block in unborn babies whose mothers have certain antibodies. Pregnant women at high risk will use a home device to check their baby's heart rate and rhythm. If a treatable early heart block is found, mothers will receive medication to t…

This study tests whether having a peer deliver blood pressure medication directly to patients' homes, combined with health technology, helps people take their pills regularly and lowers their blood pressure. About 1,140 adults with uncontrolled high blood pressure in western Keny…

This study tests whether a blood test (ctDNA) can help doctors decide when to add a third immunotherapy drug (ipilimumab) to a two-drug combination (nivolumab and relatlimab) for people with advanced melanoma. About 90 adults with metastatic or advanced melanoma will participate.…

This study looks at whether taking probiotics alongside standard treatment can improve immune markers and recovery in people with hip or knee joint infections after replacement surgery. About 152 adults aged 18-90 who need surgery and antibiotics for their infection will take eit…

This study tests whether people with HPV-positive throat cancer can safely receive lower doses of radiation if their tumors shrink quickly during treatment. About 120 participants will have their treatment plan adjusted based on early scans and blood tests. The goal is to see if …

This study looks at whether limiting when you eat each day (time-restricted eating) can help adults who have recently lost weight keep it off and avoid regaining fat. About 110 adults aged 25-65 who lost at least 5% of their body weight in the last 3 months will be randomly assig…

This study tests whether placing a cochlear implant's ground electrode near the vagus nerve behind the ear works as well as the standard placement under a muscle. Twelve adults getting a cochlear implant will participate, and their speech understanding in noise will be measured. …

This study tests a new type of radiation therapy for men with intermediate-risk prostate cancer. Using MRI guidance, doctors give a higher radiation dose to the main tumor while lowering the dose to the rest of the prostate. The goal is to improve tumor control and reduce side ef…

This study will follow 300 men with early-stage prostate cancer who choose to have high-intensity focused ultrasound (HIFU) treatment. The goal is to track how well the treatment controls cancer and what side effects occur, especially regarding urinary and sexual function. Resear…

This study is for men with a certain type of prostate cancer that is at higher risk of coming back. It compares two treatments: standard care (6 months of hormone therapy plus focused radiation) versus the same radiation alone. The goal is to see if skipping hormone therapy still…

This study compares standard ACL reconstruction surgery using a patient's own tendon to the same surgery with an added internal brace. The goal is to see if the brace leads to better knee stability and healing. Researchers will enroll 90 people aged 18-35 who need ACL surgery and…

This early-phase study tests whether adding a heat-based treatment (radiofrequency ablation) to standard chemotherapy is safe for people with advanced pancreatic cancer that hasn't spread to other organs. About 15 participants will receive the procedure via an endoscope guided by…

This study tests two ways to help Chinese immigrants with type 2 diabetes control their blood sugar. One group gets educational videos, another gets videos plus a community health worker, and a third group gets usual care. The goal is to see which approach works best for 540 part…

This study compares two ways to check blood sugar in adults with diabetes who are starting insulin for the first time when leaving the hospital. Half will wear a continuous glucose monitor (CGM) for two weeks, and the other half will use standard finger-stick testing. The goal is…

This study tests whether using portable air filters at home can improve the health and daily function of people with heart failure. Researchers will measure how far participants can walk in six minutes, along with blood pressure and heart-related blood markers. The study involves…

This study tests two oral drugs, ladarixin and sotorasib, in people with advanced non-small cell lung cancer that has a specific KRAS G12C mutation. The goal is to see if the combination is safe and helps control the cancer longer. About 40 adults will take part in this early-pha…

This study tests a new digital tool called iMatter2 that uses artificial intelligence to help people with type 2 diabetes manage their condition. About 353 patients will use the tool to track their symptoms and receive text message support, while others receive usual care. The go…

This study tests whether a culturally tailored harm reduction program helps Black and Latinx people who use drugs engage more with services and reduce opioid or stimulant use. About 200 adults who recently misused opioids or other substances will be randomly assigned to the new p…

This study tests whether belatacept, an anti-rejection drug, is safe for adults who have received a new heart. Researchers will monitor 12 participants for serious side effects like organ rejection, infections, or graft failure. The goal is to find a better way to manage the immu…

This study tests whether adding the arthritis drug sarilumab to a three-drug immunotherapy cocktail can make treatment safer and more effective for people with advanced (stage III or IV) melanoma that cannot be removed by surgery. About 105 participants will receive the combinati…

This study tests a treatment for people whose stem cell transplant did not work well or stopped working. The treatment uses a special dose of donor cells to help the body make healthy blood cells again. The study will include 21 adults and measure how well the treatment restores …

This study tests whether adding a special collagen implant (BEAR) during meniscus tear surgery leads to better healing and less pain than standard repair alone. About 80 adults with isolated meniscus tears will be randomly assigned to receive either the implant or usual care. Res…

This study looks at whether giving a monthly buprenorphine shot to people in jail who already take daily buprenorphine helps them stay on treatment after they leave. About 200 adults entering jail with an active prescription will be randomly assigned to either switch to the month…

This study tests whether a hand transplant from a deceased donor can help people who have lost part or all of one or both hands and forearms regain better function, appearance, and feeling. Up to 100 adults aged 18 to 60 will receive the transplant and be followed with exams, X-r…

This study tests whether giving a nutritional drink to patients who are malnourished before hip or knee replacement surgery can improve their blood markers of nutrition. The study will enroll 72 adults aged 55 to 95 who are scheduled for joint replacement. Researchers will measur…

This study looks at whether checking and improving nutrition before surgery can help people with inflammatory bowel disease (IBD) recover faster and have fewer problems after their operation. About 150 adults having IBD-related intestinal surgery will be offered nutritional shake…

This early-phase trial is testing a new way to deliver radiation for low-to-intermediate risk prostate cancer. Instead of many sessions, it uses just two high-dose treatments, with an extra boost to the main tumor. The goal is to see if this approach is safe and feasible for abou…

This study tests whether a smartphone tool can help people being treated for opioid addiction avoid using illicit opioids. The app predicts a patient's risk of relapse in the next week and adjusts their medication dose accordingly. Researchers will compare relapse rates between 2…

This study is testing whether transplanting a face and hands together can help people with severe injuries that standard surgery and prosthetics cannot fix. Up to 10 adults aged 18-64 with major facial and hand damage will receive the transplant. The goal is to see if the new fac…

This study looks at whether using portable air cleaners at home can improve blood sugar control and reduce inflammation in adults with prediabetes. Researchers will measure changes in glucose levels and inflammatory markers over 4 weeks. The goal is to see if reducing air polluti…

This study looks at whether special markers in the body (biomarkers) can help find lung cancer early, before symptoms start. About 3,600 people who are at high or low risk for lung cancer will give samples and get yearly CT scans. The goal is to see if biomarkers can spot cancer …

This study is testing a new, low-dose food challenge given over several days to better diagnose FPIES, a severe food allergy that causes vomiting and diarrhea. Researchers want to find the safest and most effective dose to trigger symptoms in a controlled setting. The study will …

This study tests a modified MRI technique to reduce image distortion caused by metal hip implants. About 22 adults with a painful hip replacement will get both a standard and an optimized MRI to see which one shows clearer images. The goal is to help doctors better see bones, ten…

This study aims to prevent mental health problems by training teachers to support students' mental wellbeing and manage their own stress. About 1,556 participants, including teachers and school staff, will test a new two-level training model that uses digital learning to reach mo…

This study compares two methods to increase cancer screening rates for breast, cervical, and colorectal cancer in New York City. About 2,160 adults who are due for screening will either receive culturally tailored education materials alone or those materials plus help from a comm…

This study tests a program called Mom♥Health that helps mothers of young children lower their risk for heart disease. About 40 moms will join the program through their child's daycare center. Researchers will check if the program is easy to use and if it helps moms schedule healt…

This study tests whether the drug guselkumab can prevent psoriatic arthritis in people with psoriasis who are at high risk. About 176 adults with psoriasis will receive either guselkumab or standard care. Researchers will use ultrasound to check for early joint changes and track …

This study looks at whether the ROSE program can prevent postpartum depression in pregnant women. About 308 women receiving prenatal care at a specific clinic will take part. The program aims to reduce depressive symptoms, lower stress, and boost social support after childbirth.

This small study looks at whether combining a modified Atkins diet (low-carb, high-fat) with a regular exercise routine can improve quality of life and physical fitness in people with malignant glioma, a type of brain cancer. Fifteen participants will follow the program for 15 we…

This study tests whether using a special cuff that partly blocks blood flow during light exercise can help people with Achilles injuries get stronger and have less pain. About 57 adults aged 18 to 65 with an Achilles injury will be randomly assigned to receive either standard phy…

This study tests whether a special splint called a Relative Motion Orthosis (RMO) helps people regain finger motion after an injury better than standard treatment alone. About 64 adults with stiff finger joints will be randomly assigned to receive either standard care or standard…

This study tests a virtual program that teaches mindfulness, exercise, and nutrition to people who have had a traumatic brain injury (TBI) at least one year ago. About 138 participants will be randomly assigned to start the program right away or after a delay. The goal is to see …

This study tests whether adding extra booster sessions and a website to an 8-week mindfulness program delivered by phone can further reduce stress, anxiety, and depression in people with heart disease or risk factors. About 160 participants will be enrolled. The goal is to improv…

This study compares two 8-week telephone programs for 120 adults with epilepsy who have mild to moderate depression. One program teaches skills to manage depression, while the other offers peer support groups. Researchers will track changes in mood, quality of life, and seizures …

This study compares two wound dressings—silk fibroin and a medical glue—used after ACL reconstruction surgery. Researchers want to see which one leads to fewer skin issues like rashes, blisters, or redness. About 100 people aged 14 to 60 having ACL surgery will take part, and the…

This study tests whether freezing certain nerves (cryoablation) during total knee replacement can reduce pain and the need for opioid painkillers afterward. About 215 adults scheduled for knee replacement will be randomly assigned to receive either standard surgery or surgery plu…

This study tests whether adding an extra nerve block (IPACK) to a standard one (adductor canal block) reduces pain and the need for strong painkillers after knee realignment surgery. About 100 adults aged 18-75 will participate. The goal is to find a better way to manage post-sur…

This study tests whether a device that sends mild electrical pulses to the calf muscle can help people regain strength and function after ankle fracture surgery. Twenty adults will be randomly assigned to receive either standard physical therapy alone or physical therapy plus ele…

This study tests whether a safe, low-level electrical stimulation device used at home can slow vision loss and improve daily function in people with optic neuropathy. Researchers will enroll 70 adults with optic nerve damage to use the device every other day for 8 weeks. The goal…

This study tests whether a gentle brain stimulation technique (tDCS) combined with speech therapy can reduce stuttering severity and its negative impact on daily life. Sixteen adults who stutter will receive the treatment, and researchers will measure changes in speech fluency, a…

This study explores whether a non-invasive light treatment called transcranial photobiomodulation (tPBM) can reduce leftover sleepiness in people with obstructive sleep apnea who already use CPAP. About 22 adults with moderate to severe OSA who still feel sleepy despite good CPAP…

This study tests whether psilocybin, the active ingredient in magic mushrooms, can help people with alcohol use disorder by changing how their brain responds to alcohol cues. Two hundred adults will receive either psilocybin or a placebo, and researchers will use brain scans and …

This study tests whether a special nutritional supplement taken for three weeks after hip fracture surgery can help older adults (65+) lose less muscle and recover better. Participants are randomly assigned to receive either the supplement or standard dietary advice. The main goa…

This study tests whether a special light treatment (photobiomodulation) can reduce swelling and tissue hardening caused by radiation therapy in head and neck cancer survivors. About 60 participants who completed radiation at least 3 months ago will receive either the light treatm…

This study tests if shining a special invisible light on the forehead can change blood flow in the brains of people with major depression. About 120 adults aged 18-65 with depression will receive the light treatment. Researchers will measure brain blood flow with MRI and track mo…

This study tests whether cannabidiol (CBD) can reduce PTSD symptoms and improve thinking in 120 adults with PTSD, half of whom also have a mild traumatic brain injury. Participants take either 400 mg, 800 mg of CBD, or a placebo daily for 8 weeks. The goal is to see if CBD helps …

This study looks at whether changing the frequency settings on a cochlear implant can improve sound quality and speech understanding for people who use both a cochlear implant and a hearing aid. About 24 adults who have had their implant for at least 6 months will test two differ…

This study looks at whether Jornay PM, a medication taken at night, can help adults with ADHD manage symptoms like inattention and emotional ups and downs from morning through early evening. Researchers will track 30 adults over 10 weeks to see how well the drug works and if it i…

This study tests whether a behavioral health program started before surgery and continued for six weeks after can improve swallowing and voice in people undergoing anterior cervical discectomy and fusion (ACDF). About 50 adults will participate, using video X-rays and questionnai…

This study tests whether empagliflozin, a diabetes medication, can reduce symptoms of major depression. The drug helps the body produce ketones, which may provide an alternative energy source for the brain and improve mood. Researchers will enroll 16 adults with moderate to sever…

This study tests a non-invasive light therapy called transcranial photobiomodulation (tPBM) in 70 older adults (ages 55-85) who had a moderate to severe traumatic brain injury 1-2 years ago. The goal is to see if the light can increase blood flow to the brain and improve thinking…

This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) combined with talk therapy can reduce anxiety, depression, and existential distress in people with advanced cancer. About 200 adults with stage 3 or 4 cancer will receive either psiloc…

This study tests whether a guided mental health app called SilverCloud can help teens with depression or anxiety. About 120 high school students will either use the app or get usual care. Researchers will check if symptoms improve and if the app is easy to use in schools.

This study tests a small device that gently stimulates a nerve in the ear to see if it can safely improve nerve-related symptoms in people with chronic kidney disease. Thirty adults with stage 3-5 kidney disease will use the device for 15 minutes a day over two weeks. The main go…

This study tests if a telephone-based mindfulness program can help Black women with high blood pressure lower their numbers. Researchers will compare the mindfulness program to a support group. The goal is to see if learning to manage stress through mindfulness leads to better bl…

This study tests whether using a special cuff to briefly restrict blood flow during physical therapy can help people with certain leg injuries (like torn tendons or fractures) regain strength and muscle mass more quickly. About 128 adults aged 18-65 who need standard physical the…

This study tests a new noise reduction algorithm designed to help cochlear implant users understand speech better in noisy environments. About 60 people aged 12 and older who use a cochlear implant will listen to sentences in quiet and noisy settings, with and without the algorit…

This study tests whether a one-month program of 20 home-based brain stimulation sessions, combined with guided mindfulness meditation, can help adults aged 22-65 who want to reduce their cannabis use. Participants will be randomly assigned to receive either real or sham stimulati…

This study tests a program called RELAXaHEAD, a smartphone-based behavioral approach to help people with migraines manage their condition remotely. Researchers will enroll 356 adults who have migraines and track changes in disability and quality of life over several weeks. The go…

This study aims to understand why people struggle with self-control, especially when tempted by snacks. Researchers will ask 300 adults on a diet to decide how much they would pay to avoid tempting foods, while measuring their brain activity with MRI. The goal is to uncover the m…

This study looks at how reducing cholesterol levels changes blood clotting cells, immune cells, and blood vessel health in people with type 1 diabetes. Researchers will follow 125 participants for one to two months, taking blood samples to measure these effects. The goal is to be…

This study observes 67 adults with lumbar stenosis (a narrowing in the spine) who also have low back and leg pain for at least 12 weeks. Researchers want to see how many have a "directional preference" — meaning certain movements (like bending forward or sideways) ease their pain…

This study aims to improve how children with cochlear implants perceive sound by testing new coding strategies. Researchers will compare hearing performance between children and adults, both with and without implants. The goal is to better understand the auditory system and enhan…

This study collects samples from the airways, stool, and blood of 48 adults with advanced lung cancer who are starting immunotherapy. Researchers want to see if the types of bacteria in the lungs and gut can predict how well the treatment works. The goal is to better understand w…

This study is testing a special hearing device called an auditory brainstem implant (ABI) in up to 20 children who are deaf because they are missing the inner ear or the hearing nerve. The implant sends sound signals directly to the brainstem, bypassing the missing parts. Researc…

This study follows 1500 adults who had COVID-19 to see how the virus affects their heart and lungs over time. Researchers will track inflammation markers and breathing problems. The goal is to learn more about recovery and long-term effects, not to test a new treatment.

This study tests whether a computer program called BrainHQ can help improve memory and attention in adults who have had a traumatic brain injury (TBI). About 150 adults with mild, moderate, or severe TBI will either use BrainHQ or play regular brain games. Researchers will compar…

This study creates a national registry of 500 people diagnosed with takotsubo (broken heart) syndrome, a temporary heart condition that mimics a heart attack. Researchers will track participants over time to understand what causes it, how it affects quality of life, and what heal…

This study works with community members and NYC public hospitals to help people who don't speak English well get better access to language services. The goal is to make sure everyone can understand their care and get important preventive services like screenings and vaccines. Abo…

This study looks at how social media ads with pictures of unhealthy food, people of the same race, and 'likes' influence how many calories teenagers eat. About 480 teens aged 13-17 who use Instagram daily will take part. Researchers will track what they eat and where they look in…

This study aims to understand how the trillions of bacteria living in our bodies (the microbiome) are linked to cancer and heart disease. Researchers will collect samples and health information from 16,000 adults over age 40. The goal is to build a large database that can help fu…

This study looks at how the hippocampus, a brain area important for memory, behaves when people explore what they see. Researchers will record brain activity in epilepsy patients who already have electrodes implanted for medical reasons. The goal is to understand brain signals du…

This study looks at how community-centered safety models—like co-response teams or violence intervention programs—affect violence among youth and young adults in U.S. cities. Researchers will compare data from 15 locations before and after these programs start. The goal is to see…

This study is testing a mobile health toolkit called mWEL to help teachers and parents in Uganda better understand and manage their mental health. The toolkit provides self-help support, with extra help from community health workers if needed. The study will measure changes in me…

This study tests a mobile app called GeriKit to gather more information about older adults (75+) with ischemic heart disease. Researchers want to see if the app helps them better understand patients' health and outcomes, like hospital readmission or quality of life. About 150 peo…

This study is looking for biological markers (biomarkers) that can show whether phage therapy is working against hard-to-treat bacterial lung infections. Researchers will collect blood and airway samples from 100 adults with nontuberculous mycobacterial lung disease who are being…

This early-phase study looks at how the drug belzutifan changes a protein called CAIX in clear cell kidney cancer. About 12 people with advanced cancer that has worsened after immunotherapy will get belzutifan and have special PET scans before and after treatment. The goal is to …

This small study is testing a device that gently stimulates a nerve in the ear to see if it is safe and tolerable for people with chronic kidney disease (CKD). The goal is to gather early data on how the device affects heart rate and blood pressure, which may help design future s…

This study looks back at the records of 2,000 adults who had surgery for a pancreatic condition called IPMN, which can turn into cancer. Researchers want to understand why surgery was done and how often cancer was found by accident. The goal is to help doctors better predict whic…

This study collects medical records, family histories, and DNA from children aged 11 months to 18 years who died suddenly and without clear cause. Researchers hope to identify risk factors and causes to help prevent future tragedies. The study does not offer treatment but aims to…

This study explores whether heart rate measurements from a brain-stimulating headset can help predict how well people with mild to moderate depression respond to treatment. One hundred participants will receive either real or fake brain stimulation at home for 10 days. The goal i…

This study looks at how stress, anxiety, and negative feelings affect learning and decision-making. Researchers will measure how people value rewards and predict emotions. About 200 adults aged 18-65, including some with generalized anxiety disorder, will complete tasks and surve…

This research looks at how social media ads affect the food choices and calorie intake of Black and White teenagers aged 13 to 17. Participants will view ads and then make food purchases or eat in a controlled setting. The goal is to understand how ad features like images and 'li…

This study tests a culturally tailored education program to help more people get screened for colorectal cancer. About 50 adults aged 45-75 who are not up-to-date on screening will participate. The goal is to see if the program is practical, well-liked, and effective at increasin…

This study aims to help people with small kidney tumors (up to 4 cm) make informed decisions about their treatment. Researchers will develop a decision aid that explains the benefits and risks of each option based on the patient's own situation. The study will enroll 40 adults an…

This study looks at whether a new quality measurement strategy can help improve treatment for people with opioid use disorder in New York State. Researchers will interview patients, families, and providers, and survey clinics to see how the strategy affects care. About 35 clinics…

This study looks at how well a virtual oncology program works for veterans newly diagnosed with lung, colorectal, prostate, or breast cancer. Researchers will track telehealth visits, quality of care, and costs over 36 months. The goal is to see if this program helps veterans get…

This study follows people with familial dysautonomia (FD), a rare nerve disorder, to learn how the disease changes over time. Researchers will collect routine medical test results and optional blood samples to create a detailed database. The goal is to find biological markers tha…

This study looks at whether a special type of scan (PSMA PET/MRI) is better than a standard MRI at finding prostate cancer that comes back after a treatment called High-Intensity Focused Ultrasound (HIFU). About 60 men who have had HIFU for localized prostate cancer will get both…

This study looks at whether a digital visual communication tool can help newly diagnosed cancer patients, their caregivers, and doctors better understand treatment choices. About 86 adults with breast or head and neck cancer will use the tool and then report their satisfaction. T…

This study looks at whether people with chronic hepatitis B who have undetectable virus levels in their blood also have undetectable virus in other body fluids like saliva or semen. If true, it could support the message that undetectable means untransmissible (U=U) for hepatitis …

This research study looks at how children and adults with cochlear or auditory brainstem implants understand speech and other sounds. Participants will listen to words, sentences, and tones, and researchers will measure how accurately they identify them. The goal is to better und…

This study looks at how breathing in dust from the World Trade Center collapse may cause heart and lung problems in FDNY first responders. Researchers will measure blood markers and lung function in 100 retired or light-duty firefighters. The goal is to better understand these he…

This study tests whether a non-invasive light sensor (NIRS) can detect early signs of kidney injury in babies born before 30 weeks. Researchers will monitor oxygen levels in the kidneys over the first week of life and track health outcomes. The goal is to find a better way to pre…

This study looks at the bacteria living in the lungs of people with a chronic lung condition called bronchiectasis, who may also have an infection from NTM bacteria. Researchers will collect sputum and airway samples from 200 participants to compare the lung microbiome of those w…

This study collects blood from 350 people who have had a heart attack, plus some with stable heart disease, to examine how platelets behave. Researchers want to understand differences between men and women and what makes platelets more active. No new treatments are tested; the go…

This study looks at how people with hearing loss in one ear adapt to a cochlear implant. Participants will try four different sound maps during their first month after the implant is turned on. The goal is to see if changing the low-pitch settings helps them hear better in noisy …

This study looks at ways to help researchers, families, and community members work together better in child health research. It will involve about 480 people from different research teams. The goal is to see if special teamwork strategies lead to better study results, like reachi…

This study aims to find ways to predict which people with chronic pancreatitis will get pain relief from a procedure called endoscopic therapy. Researchers will use brain tests, pain sensitivity tests, and questionnaires before the procedure. They will then follow 100 adults for …

This study focuses on making it easier for parents of children with multiple chronic conditions or technology dependence to care for them after a hospital stay. Researchers will check how well parents understand and follow discharge instructions, and track any health problems lik…

This study looks at whether teaching patients and their doctors about side effects from certain breast cancer drugs (called antibody drug conjugates) can improve how those side effects are managed. About 30 breast cancer patients and their clinicians will take part. The goal is t…

This study works with the Ramapough Native American community to understand how environmental pollution affects their health and nutrition. Researchers will test soil, water, and blood or urine samples from about 400 adults to measure heavy metals and key nutrients. The goal is t…

This study tests whether giving magnesium sulfate soon after a cardiac arrest can help protect the brain. Researchers will enroll 178 adults who regained a pulse within 2 hours. The main goal is to see if the treatment is safe and practical, not yet to prove it works. Results wil…

This study looks at whether seeing TikTok influencers with food makes kids ages 10-13 buy more calories. About 100 participants will watch influencer posts and then pick snacks in a pretend online store. The goal is to understand how food ads on social media affect youth eating h…

This study looks at how mindfulness-based stress reduction (MBSR) affects brain activity in people with generalized anxiety disorder (GAD). Researchers will compare MBSR to a stress education program in 150 adults aged 18–50. They will use brain scans and other measures to unders…

This study looks at how adults with cochlear implants understand speech in everyday situations. Researchers will measure listening effort and comprehension through various tests, including word recognition and story recall. The goal is to find what helps or hinders communication …

This study looks at how difficult childhood experiences impact the course of multiple sclerosis (MS). Researchers will work with 300 young adults with relapsing-remitting MS, most of whom are Black, Hispanic, or from low-income backgrounds. Participants will have MRI scans and bl…

This study looks at the bacteria living in the lungs of smokers who have early-stage COPD and those who don't. Researchers want to understand how these bacteria and the body's immune response are linked to the disease. About 230 smokers will take part, providing samples through a…

This study looks at why some people newly diagnosed with diabetes in the emergency room don't get the follow-up care they need. Researchers will review medical records, interview patients, and test whether telehealth visits can help connect them to a regular doctor. The goal is t…

This study looks at how the number of 'likes' on social media food ads affects what Black and White teenagers (ages 13-17) choose to buy for snacks. Researchers will show different ads and track the calories teens pick in a hypothetical shopping game. The goal is to understand if…

This study creates a database to record how well freezing therapy (cryotherapy) works for men with early-stage prostate cancer that hasn't spread. Researchers will track 1,000 participants over time to see how long they live without their PSA levels rising. The goal is to better …

This study looks at whether it's practical and acceptable to offer genetic testing for cancer-related genes to all women aged 25-39 visiting a gynecology clinic, instead of requiring a specialist referral. Researchers will track how many women choose to get tested and how many ha…

This study aims to understand how the brain creates the feeling of wanting to move. Researchers will use safe, non-invasive techniques like brain stimulation and EEG to measure brain activity in 30 people—both healthy volunteers and patients with psychogenic movement disorders or…

This study looks at how harm reduction programs in New York City homeless shelters affect overdose deaths and health care use. Researchers will analyze data from shelter records, Medicaid, and death records for people who stayed in shelters between 2021 and 2026. No direct contac…

This study looks at how exercise affects the brain in adults with anxiety disorders. Researchers will measure specific brain chemicals from blood samples to understand the link between physical activity and reduced anxiety. The study involves 30 sedentary adults aged 18-50, some …

This study looks at how seeing food ads in virtual reality (VR) changes snacking, hunger, and desire to buy food in Black and white young adults aged 18-24. Participants will be randomly assigned to watch either food ads or non-food content in VR. Afterward, their snack eating, h…