Magic mushroom compound tested to help opioid users who relapse on methadone

NCT ID NCT06796062

Recruiting now Disease control Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

First seen Jan 10, 2026 · Last updated May 24, 2026 · Updated 23 times

Summary

This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) can help people with opioid addiction who still use illegal opioids despite being on methadone. About 240 participants will receive either a high, medium, or low dose of psilocybin and be followed for 24 weeks. The goal is to see if psilocybin reduces opioid use and cravings safely.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Duke City Recovery Toolbox
RECRUITING

Albuquerque, New Mexico, 87102, United States
NYU Langone Health
RECRUITING

New York, New York, 10016, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
StartCare
RECRUITING

Brooklyn, New York, 11206, United States
University of New Mexico
RECRUITING

Albuquerque, New Mexico, 87106, United States
VIP Community Services, Inc
RECRUITING

The Bronx, New York, 10457, United States

Conditions

Explore the condition pages connected to this study.

OPIOID USE DISORDER