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Can exercise boost brain and body health during opioid treatment?

NCT ID NCT04496934

Symptom relief Sponsor: Haukeland University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 18, 2026 · Last updated Sep 18, 2026

Summary

Researchers are testing whether a 12-week exercise program can improve thinking skills, physical fitness, and quality of life for adults in opioid substitution therapy. Participants are randomly assigned to start exercise right away or after a 12-week wait. The study measures changes in endurance, strength, balance, and cognitive function over up to a year.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a 12-week exercise program with a training contact
What this could lead to
If exercise helps, it could become a low-cost add-on to opioid substitution therapy that supports both physical and mental health.
What could go wrong
The trial is small and early, so any benefits may be modest or not hold up in larger studies. Exercise carries typical risks like muscle soreness or injury, and participants must be stable on their medication.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

17 people

The number who actually took part.

Started

Jan 2018

Finished

Dec 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants must sign a informed consent form * Must be participating in an opioid substitution program * Must be on a steady fixed dose of medication * Must be at least 18 years of age Exclusion Criteria: * Pregnancy * Being in opioid substitution program for less than three months

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Conditions

The condition(s) this trial relates to.

opiate dependence substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Opioid dependence Opioid-use disorder Substance use disorders

Contacts and locations

Locations

  • Haukeland University Hospital

    Bergen, Norway

More trials for these conditions

Other studies related to the condition(s) this trial covers.