Nyu Langone Health

This study tests whether a potassium-containing salt substitute is safe for people with end-stage kidney disease on hemodialysis. Twenty participants will use the salt substitute for 16 days and regular table salt for 16 days, with potassium levels checked regularly. The goal is …

This study tests a program that combines online diabetes education videos with help connecting to social services for low-income Chinese and Latino/a immigrants with type 2 diabetes. About 480 adults aged 18-70 with high blood sugar will take part. The goal is to see if this appr…

This study tests if a drug called emapalumab can prevent severe side effects (cytokine release syndrome and nerve toxicity) caused by bispecific antibody therapy for lymphoma and multiple myeloma. About 60 adults will receive emapalumab before starting their cancer treatment. The…

This study will adapt a community health worker-led program to include mental health support for South Asians with type 2 diabetes who are at risk for depression. About 100 participants will try the program, which includes digital tools and a trauma-informed approach. The goal is…

This early-phase study tests whether a new radiation technique, guided by real-time MRI and tumor biology, can safely deliver higher doses to aggressive brain tumors (grade 3 or 4 gliomas). About 20 adults with newly diagnosed tumors will receive targeted radiation using an MR-Li…

This study tests a personalized diet program for Chinese and Vietnamese Americans with type 2 diabetes. Participants use a continuous glucose monitor to track blood sugar, and those who don't improve after 4 weeks get extra dietary coaching. The goal is to see if this approach he…

This early-phase study tests a new type of radiation (lattice radiotherapy) combined with chemotherapy and immunotherapy before surgery for advanced oral cavity cancer. About 30 adults with resectable tumors will receive different radiation doses to find the safest and most effec…

This study will test a program that helps supportive housing agencies use proven methods to prevent overdoses and improve tenant health. About 24 agencies in New York and New Jersey will take part, with around 2,940 tenants involved. The goal is to see if this approach can reduce…

This study tests a program called LINKED that uses social networks to encourage people who inject drugs to start HIV prevention medication (PrEP) and addiction treatment (MOUD). About 398 participants will be split into two groups: one gets the LINKED program, the other gets gene…

This study tests three different high-intensity walking training programs in 20 stroke patients during inpatient rehab. The goal is to find which approach best improves balance, walking speed, and endurance. Participants will be randomly assigned to one of the three programs, and…

This study looks at whether virtual Reiki therapy can help ease pain and improve quality of life for people with lupus. Twenty adults with lupus will continue their usual care and also receive one virtual Reiki session each week for 8 weeks. Researchers will measure changes in pa…

This study looks at whether using a weighted blanket before and after total knee replacement surgery can help reduce anxiety and pain. Thirty adults having knee replacement at NYU Langone will either get a weighted blanket or a regular blanket. The goal is to see if patients find…

This study tests whether an implanted nerve stimulator (Altius®) can reduce persistent pain in people who have had a leg amputation and still feel pain after nerve surgery. About 32 adults will get the device and be followed for changes in pain, how often they use their prostheti…

This study looks at whether a safe, mild brain stimulation technique called tDCS can help adults with moderate depression sleep better and feel better. Participants will use a home-based device and track their sleep and mood changes. The goal is to see if better sleep leads to fe…

This study tests whether a home-based telerehabilitation program using the Band Connect app works as well as in-person physical therapy for people recovering from rotator cuff repair surgery. About 68 adults will be randomly assigned to either traditional rehab or the app-based p…

This study tests whether taking tranexamic acid pills for 7 days after knee replacement surgery helps reduce pain, improve function, and speed recovery. About 350 adults having their first knee replacement will receive either the drug or a placebo. Researchers will track their pr…

This study tests whether a gel called Barrigel can safely protect the rectum during cryoablation, a treatment that freezes prostate cancer. About 20 men with localized or recurrent prostate cancer will receive the gel before the freezing procedure. The main goal is to see if the …

This study compares two types of lasers used to break up kidney stones during a procedure called ureteroscopy. Researchers want to see which laser is safer and more effective at removing stones. About 70 adults with kidney stones between 7 and 20 mm will take part.

This early study tests whether a single high dose of psilocybin (the active ingredient in magic mushrooms) combined with talk therapy can help people with severe irritable bowel syndrome (IBS). Ten adults with persistent IBS symptoms will receive either psilocybin or a placebo (n…

This early study will give 25 adults who stutter a single dose of psilocybin (the active ingredient in magic mushrooms) along with therapy. Researchers want to see if it safely reduces stuttering severity and struggle, and how it changes brain activity. The goal is to find out if…

This study tests a new 3D-printed device that measures how balanced the knee is during total knee replacement surgery. About 50 adults having their first knee replacement will take part. Surgeons will use the device alongside their usual methods, but it won't change how they perf…

This study examines blood vessel health in 250 adults who have chest pain but no major blockages in their heart arteries, a condition called INOCA. Researchers will compare vessel cells from the heart and arm to see how they relate to symptoms and daily function. Participants wil…

This study looks at how vision loss changes the way people move and think during everyday activities like walking and finding objects. Researchers will test a wearable system called VIS4ION that gives touch and sound cues to help people with low vision. The study includes 150 adu…

This study will follow over 5,000 adults with Long COVID for two years to see if their symptoms get better, stay the same, or lead to new health problems like heart disease or chronic fatigue. Researchers will track symptoms like brain fog and fatigue using surveys and health rec…

This study looks at whether using only a head drape during pediatric tonsillectomy leads to more infections than full-body draping. About 200 children under 18 will be randomly assigned to one of the two methods. Researchers will also measure waste and costs to see if a simpler s…

This study will follow 75 adults aged 18-75 with Crohn's disease or ulcerative colitis who are starting guselkumab treatment. The goal is to see how the drug affects joint pain and stiffness related to spondyloarthritis over one year. Participants will report their symptoms throu…

This study is testing a new AI-powered tool called AIManage that helps doctors and patients manage medications for diabetes and obesity. The tool will provide guidance on adjusting doses. The study involves 16 participants and will first gather feedback on how useful and easy the…

This study looks at how young children with neurofibromatosis type 1 (NF1) walk, to see if simple walking tests can predict future movement difficulties. Researchers will measure walking speed and other skills in 56 children under 6 years old. No treatment is given; the goal is t…

This study looks at whether showing people a real-time visual display of their swallowing pressure helps them perform swallowing exercises more effectively. Fifty healthy adults aged 18-40 will swallow with and without this visual feedback while a thin tube measures their throat …

This study tests a new, ultra-fast lab test (called UR-ddPCR) that can detect leftover IDH1-mutant tumor cells during brain surgery. If the test finds any remaining cancer cells, the surgeon can remove more tissue right away. The goal is to see if this approach helps people with …

This study will test a new tool called Communication Compass that gives doctors-in-training quick, personalized feedback on how they talk with and educate patients. About 120 medical residents will take part to see if the tool helps improve their communication skills. The goal is…

This pilot study will test whether it is possible to collect health information from people taking part in a community food program in Brooklyn. The program provides fresh produce to English-, Chinese-, and Spanish-speaking adults for 20 weeks each year. Researchers will measure …

This study tests whether a simple nudge—a reminder built into the electronic health record—can help doctors follow guidelines when ordering CT scans for pulmonary embolism (a blood clot in the lung). About 440 doctors across 10 emergency departments will be studied over 33 months…

This study looks at whether a program called PlayReadVIP can help family child care providers support children's learning and development. About 240 providers will try the program, and researchers will measure changes in their confidence, the children's literacy activities, and t…

This study will look at how using overdose prevention centers (places where people can use drugs under supervision) affects the risk of fatal and non-fatal overdoses and mental health crises. Researchers will follow 500 adults in New York City who use multiple substances and visi…

This early-phase study will look at how aspirin affects blood platelets in pregnant women at risk for preeclampsia. About 30 participants will take 81 mg of aspirin twice a day, and blood samples will be collected about 4 weeks later to measure platelet activity. The goal is to b…

This study will test a new imaging tool called ATEC IOA during spinal deformity surgery in 40 adults. The goal is to see if it gives more precise measurements than standard X-rays to help surgeons better align the spine. Participants will have their spine images compared before, …